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Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density
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Winston, Anthony P., Alwazeer, Ahmed E. F. and Bankart, Michael J. G.. (2008) Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density. International Journal of Eating Disorders, Vol.41 (No.3). pp. 284-287. ISSN 0276-3478
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Official URL: http://dx.doi.org/10.1002/eat.20501
Abstract
Objective: Decreased bone mineral density (BMD) in anorexia nervosa (AN) can be detected easily by dual-energy Xray absorptiometry (DXA). This study was designed to assess the prevalence of osteoporosis and osteopenia in AN, identify predictors, and determine the diagnostic yield of screening with DXA. Method: DXA was used to screen 59 unselected adult patients with a history of AN. Results: Osteoporosis was identified in 18 patients (31%) and osteopenia in 30 (51%). The spine had a lower mean T-score than either the hip or femur. BMI significantly predicted T-score (p = 0.0006) and the odds of having osteoporosis (p = 0.0188). There was a significant association between use of oestrogens and the presence of osteoporosis or osteopenia (p = 0.0491). There was no significant association between duration of AN and T-score. A duration of AN of less than 1 year was found in 12% of those with osteoporosis. Conclusion: BMI is a strong predictor of BMD in AN. DXA is an effective screening tool and should probably be offered routinely. (c) 2008 by Wiley Periodicals, Inc.
| Item Type: | Journal Article |
|---|---|
| Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Faculty of Medicine > Warwick Medical School |
| Journal or Publication Title: | International Journal of Eating Disorders |
| Publisher: | John Wiley & Sons |
| ISSN: | 0276-3478 |
| Date: | April 2008 |
| Volume: | Vol.41 |
| Number: | No.3 |
| Number of Pages: | 4 |
| Page Range: | pp. 284-287 |
| Identification Number: | 10.1002/eat.20501 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| URI: | http://wrap.warwick.ac.uk/id/eprint/30375 |
Data sourced from Thomson Reuters' Web of Knowledge
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