Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density
Winston, Anthony P., Alwazeer, Ahmed E. F. and Bankart, Michael J. G.. (2008) Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density. International Journal of Eating Disorders, Volume 41 (Number 3). pp. 284-287. ISSN 0276-3478Full text not available from this repository.
Official URL: http://dx.doi.org/10.1002/eat.20501
Objective: Decreased bone mineral density (BMD) in anorexia nervosa (AN) can be detected easily by dual-energy Xray absorptiometry (DXA). This study was designed to assess the prevalence of osteoporosis and osteopenia in AN, identify predictors, and determine the diagnostic yield of screening with DXA.
Method: DXA was used to screen 59 unselected adult patients with a history of AN.
Results: Osteoporosis was identified in 18 patients (31%) and osteopenia in 30 (51%). The spine had a lower mean T-score than either the hip or femur. BMI significantly predicted T-score (p = 0.0006) and the odds of having osteoporosis (p = 0.0188). There was a significant association between use of oestrogens and the presence of osteoporosis or osteopenia (p = 0.0491). There was no significant association between duration of AN and T-score. A duration of AN of less than 1 year was found in 12% of those with osteoporosis.
Conclusion: BMI is a strong predictor of BMD in AN. DXA is an effective screening tool and should probably be offered routinely. (c) 2008 by Wiley Periodicals, Inc.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
|Divisions:||Faculty of Medicine > Warwick Medical School|
|Library of Congress Subject Headings (LCSH):||Osteoporosis -- Diagnosis, Anorexia nervosa -- Patients -- Medical examination, Medical screening, Dual-energy X-ray absorptiometry, Bone densitometry|
|Journal or Publication Title:||International Journal of Eating Disorders|
|Publisher:||John Wiley & Sons|
|Official Date:||April 2008|
|Number of Pages:||4|
|Page Range:||pp. 284-287|
|Access rights to Published version:||Restricted or Subscription Access|
1. Kovacs D, Winston AP. Physical assessment of patients with anorexia
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