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TreeMos : a high-throughput phylogenomic approach to find and visualize phylogenetic mosaicism
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Moore, Jonathan D. and Allaby, Robin G. (2008) TreeMos : a high-throughput phylogenomic approach to find and visualize phylogenetic mosaicism. Bioinformatics, Vol.24 (No.5). pp. 717-718. doi:10.1093/bioinformatics/btn027 ISSN 1367-4803.
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Official URL: http://dx.doi.org/10.1093/bioinformatics/btn027
Abstract
TreeMos is a novel high-throughput graphical analysis application that allows the user to search for phylogenetic mosaicism among one or more DNA or protein sequence multiple alignments and additional unaligned sequences. TreeMos uses a sliding window and local alignment algorithm to identify the nearest neighbour of each sequence segment, and visualizes instances of sequence segments whose nearest neighbour is anomalous to that identified using the global alignment. Data sets can include whole genome sequences allowing phylogenomic analyses in which mosaicism may be attributed to recombination between any two points in the genome. TreeMos can be run from the command line, or within a web browser allowing the relationships between taxa to be explored by drill-through.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software Q Science > QD Chemistry T Technology > TP Chemical technology Q Science > QH Natural history > QH301 Biology Q Science > QA Mathematics |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) > Warwick HRI (2004-2010) | ||||
Journal or Publication Title: | Bioinformatics | ||||
Publisher: | Oxford University Press | ||||
ISSN: | 1367-4803 | ||||
Official Date: | 1 March 2008 | ||||
Dates: |
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Volume: | Vol.24 | ||||
Number: | No.5 | ||||
Number of Pages: | 2 | ||||
Page Range: | pp. 717-718 | ||||
DOI: | 10.1093/bioinformatics/btn027 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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