Bhattacharyay, A. (2008) A simple model for dynamic phase transitions in cell spreading. Journal of Physics A: Mathematical and Theoretical, Volume 41 (Number 5). Article No. 055101. doi:10.1088/1751-8113/41/5/055101 ISSN 1751-8113.

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Abstract

There are some interesting experimental results on cell spreading at macroscopic scales (cell size) where people have observed various dynamic phases in terms of rate of spreading of area of adherence to the substrate. In the present paper, we develop a very simple phenomenological model to capture those apparent dynamic phases of a spreading cell without going into the microscopic details of actin polymerization which is the main driving force for such processes. Our conclusion is that the dynamic phases of cell spreading depend on some gross parameters of the cell rather than on complex signalling pathways.

Item Type:	Journal Article
Subjects:	Q Science > QC Physics Q Science > QH Natural history
Divisions:	Faculty of Science, Engineering and Medicine > Science > Chemistry
Library of Congress Subject Headings (LCSH):	Phase transformations (Statistical physics), Cells -- Motility
Journal or Publication Title:	Journal of Physics A: Mathematical and Theoretical
Publisher:	IOP Publishing Ltd
ISSN:	1751-8113
Official Date:	8 February 2008
Dates:	Date Event 8 February 2008 Published
Volume:	Volume 41
Number:	Number 5
Number of Pages:	7
Page Range:	Article No. 055101
DOI:	10.1088/1751-8113/41/5/055101
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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