Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Quantification of lung injury using ventilation and perfusion distributions obtained from gamma scintigraphy

Tools
- Tools
+ Tools

Brook, B. S., Murphy, C. M., Breen, D., Miles, A. W., Tilley, D. G. and Wilson, A. J. (2007) Quantification of lung injury using ventilation and perfusion distributions obtained from gamma scintigraphy. Physiological Measurement, Vol.28 (No.12). pp. 1451-1464. doi:10.1088/0967-3334/28/12/001

Research output not available from this repository.

Request-a-Copy directly from author or use local Library Get it For Me service.

Official URL: http://dx.doi.org/10.1088/0967-3334/28/12/001

Request Changes to record.

Abstract

This paper explores the potential of isotope V/Q lung scans to quantify lung disease. Areas of restricted perfusion in subjects with a pulmonary embolus (PE) were identified in 3D reconstructions of V/Q images achieved using anatomical data from the Visible Human Project. From these, the extent of lung damage was quantified. Significant differences in the values of both LogSD V and LogSDQ (p > 0.05) obtained from plots of V and Q against Log(V/Q) were found between normal subjects and subjects with a PE, but no correlation was found between either of these parameters and the degree of lung damage in subjects with a PE (p > 0.05). Whilst V/Q values were lognormally distributed, the V/Q distributions from the subjects with a PE failed to show the bimodal distribution predicted from theoretical considerations and MIGET measurements previously reported. There was a statistically significant difference in the mean and standard deviation values of the V/Q distributions between normal subject and subjects with a PE (p < 0.05) but not in the median values (p > 0.05). There was no correlation between the mean, median and standard deviation of the distributions from the subjects with a PE and the percentage of damage present (p > 0.05).

Item Type: Journal Article
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine
Q Science > QP Physiology
Divisions: Faculty of Science, Engineering and Medicine > Science > Physics
Journal or Publication Title: Physiological Measurement
Publisher: Institute of Physics Publishing Ltd.
ISSN: 0967-3334
Official Date: December 2007
Dates:
DateEvent
December 2007Published
Volume: Vol.28
Number: No.12
Number of Pages: 14
Page Range: pp. 1451-1464
DOI: 10.1088/0967-3334/28/12/001
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item
twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us