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Delusion formation and reasoning biases in those at clinical high risk for psychosis

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Broome, Matthew R., Johns, L. C., Valli, Isabel, Woolley, J. B., Tabraham, P., Brett, C., Valmaggia, L., Peters, E., Garety, P. A. and McGuire, Philip. (2007) Delusion formation and reasoning biases in those at clinical high risk for psychosis. British Journal of Psychiatry, Vol.191 (Suppl. 51). S38-S42. ISSN 0007-1250

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Official URL: http://dx.doi.org/10.1192/bjp.191.51.s38

Abstract

Background Cognitive models propose that faulty appraisal of anomalous experiences is critical in developing psychosis, particularly delusions. A data gathering bias may be fundamental to abnormal appraisal. Aims To examine whether there is a data gathering bias in people at high risk of developing psychosis. Method Individuals with an at-risk mental state (n=35) were compared with a matched group of healthy volunteers (n=23). Participants were tested using a modified version of the 'beads' reasoning task with different levels of task difficulty. Results When task demands were high, the at-risk group made judgements on the basis of less information than the control group (P < 0.05).Within both groups, jumping to conclusions was directly correlated with the severity of abnormal beliefs and intolerance of uncertainty (P < 0.05). In the at-risk group it was also associated with impaired working memory (P < 0.05), whereas in the control group poor working memory was associated with a more conservative response style (P < 0.05). Conclusions People with an at-risk mental state display a jumping to conclusions reasoning style, associated with impaired working memory and intolerance of uncertainty This may underlie a tendency to develop abnormal beliefs and a vulnerability to psychosis.

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing
Faculty of Medicine > Warwick Medical School
Journal or Publication Title: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Date: December 2007
Volume: Vol.191
Number: Suppl. 51
Number of Pages: 5
Page Range: S38-S42
Identification Number: 10.1192/bjp.191.51.s38
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
URI: http://wrap.warwick.ac.uk/id/eprint/30835

Data sourced from Thomson Reuters' Web of Knowledge

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