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Account : chemical cross-linking. and mass spectrometry as structure determination tools
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Novak, Petr and Giannakopulos, Anastassios E. (2007) Account : chemical cross-linking. and mass spectrometry as structure determination tools. European Journal of Mass Spectrometry, Volume 13 (Number 2). pp. 105-113. doi:10.1255/ejms.868 ISSN 1469-0667.
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Official URL: http://dx.doi.org/10.1255/ejms.868
Abstract
Chemical cross-linking is becoming a valuable tool for the high-order structure determination of proteins and protein complexes. Cross-linking methodology is able to provide low-resolution structures when at least something is known already about the proteins under investigation. The suitability of top-down and bottom-up methodologies is discussed and further potential applications of chemical cross-linking of proteins, as well as combinations with other techniques such as hydrogen/deuterium exchange and molecular modeling, are suggested.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QC Physics | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Journal or Publication Title: | European Journal of Mass Spectrometry | ||||
Publisher: | I M Publications | ||||
ISSN: | 1469-0667 | ||||
Official Date: | 2007 | ||||
Dates: |
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Volume: | Volume 13 | ||||
Number: | Number 2 | ||||
Number of Pages: | 9 | ||||
Page Range: | pp. 105-113 | ||||
DOI: | 10.1255/ejms.868 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published |
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