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Using the Man9(GlcNAc)2 – DC-SIGN pairing to probe specificity in photochemical immobilization
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Dilly, Suzanne J., Clark, A. J. (Andrew J.), Mitchell, Daniel Anthony, Marsh, A. (Andrew) and Taylor, Paul C.. (2011) Using the Man9(GlcNAc)2 – DC-SIGN pairing to probe specificity in photochemical immobilization. Molecular BioSystems, Vol.7 (No.1). pp. 116-118. ISSN 1742-206X
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Official URL: http://dx.doi.org/10.1039/C0MB00118J
Abstract
We demonstrate the expected preference of an immobilised oligosaccharide Man(9)(GlcNAc)(2) upon a 96-well photochemical array, for its known receptor, the cell-surface lectin Dendritic Cell-Specific ICAM3 Grabbing Nonintegrin (DC-SIGN) when compared to immobilised competing monosaccharides.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Chemistry Faculty of Medicine > Warwick Medical School |
| Library of Congress Subject Headings (LCSH): | Oligosaccharides, Lectins, Immobilized cells |
| Journal or Publication Title: | Molecular BioSystems |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1742-206X |
| Date: | 1 January 2011 |
| Volume: | Vol.7 |
| Number: | No.1 |
| Page Range: | pp. 116-118 |
| Identification Number: | 10.1039/c0mb00118j |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Funder: | Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) |
| Grant number: | 88/EGM17690 (BBSRC & EPSRC), BB/C524338/1 (BBSRC) |
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| URI: | http://wrap.warwick.ac.uk/id/eprint/3197 |
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