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Using the Man9(GlcNAc)2 – DC-SIGN pairing to probe specificity in photochemical immobilization

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Dilly, Suzanne J., Clark, A. J. (Andrew J.), Mitchell, Daniel Anthony, Marsh, A. (Andrew) and Taylor, Paul C.. (2011) Using the Man9(GlcNAc)2 – DC-SIGN pairing to probe specificity in photochemical immobilization. Molecular BioSystems, Vol.7 (No.1). pp. 116-118. ISSN 1742-206X

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Official URL: http://dx.doi.org/10.1039/C0MB00118J

Abstract

We demonstrate the expected preference of an immobilised oligosaccharide Man(9)(GlcNAc)(2) upon a 96-well photochemical array, for its known receptor, the cell-surface lectin Dendritic Cell-Specific ICAM3 Grabbing Nonintegrin (DC-SIGN) when compared to immobilised competing monosaccharides.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science > Chemistry
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Oligosaccharides, Lectins, Immobilized cells
Journal or Publication Title: Molecular BioSystems
Publisher: Royal Society of Chemistry
ISSN: 1742-206X
Date: 1 January 2011
Volume: Vol.7
Number: No.1
Page Range: pp. 116-118
Identification Number: 10.1039/c0mb00118j
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Grant number: 88/EGM17690 (BBSRC & EPSRC), BB/C524338/1 (BBSRC)
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URI: http://wrap.warwick.ac.uk/id/eprint/3197

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