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Close contact fluctuations : the seeding of signalling domains in the immunological synapse
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Chattopadhyay, Amit K. and Burroughs, Nigel John (2007) Close contact fluctuations : the seeding of signalling domains in the immunological synapse. EPL (Europhysics Letters), Volume 77 (Number 4). doi:10.1209/0295-5075/77/48003 ISSN 0295-5075.
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Official URL: http://dx.doi.org/10.1209/0295-5075/77/48003
Abstract
We analyse the size and density of thermally induced regions of close contact in cell : cell contact interfaces within a harmonic potential approximation, estimating these regions to be below one-tenth of a micron across. Our calculations indicate that as the distance between the close contact threshold depth and the mean membrane-membrane separation increases, the density of close contact patches decreases exponentially while there is only a minimal variation in their mean size. The technique developed can be used to calculate the probability of first crossing in reflection symmetry violating systems.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QC Physics | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Mathematics | ||||
Journal or Publication Title: | EPL (Europhysics Letters) | ||||
Publisher: | Institute of Physics Publishing Ltd. | ||||
ISSN: | 0295-5075 | ||||
Official Date: | 5 February 2007 | ||||
Dates: |
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Volume: | Volume 77 | ||||
Number: | Number 4 | ||||
Number of Pages: | 5 | ||||
DOI: | 10.1209/0295-5075/77/48003 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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