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Frequency of albuminuria in primary care: a cross-sectional study

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Bramlage, Peter, Pittrow, David, Lehnert, Hendrik, Hoefler, Michael, Kirch, Wilhelm, Ritz, Eberhard and Wittchen, Hans-Ulrich. (2007) Frequency of albuminuria in primary care: a cross-sectional study. European Journal of Cardiovascular Prevention & Rehabilitation, Vol.14 (No.1). pp. 107-113. ISSN 1741-8267

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Official URL: http://dx.doi.org/10.1097/01.hjr.0000224489.03221....

Abstract

Background We aimed to assess the point prevalence of microalbuminuria (MAU) in a sample of unselected consecutive primary-care attendees, with particular focus on patients with diabetes mellitus (with and without additional concomitant diseases) and those with hypertension. Design Cross-sectional observational study in a nationwide representative sample of 1912 primary-care practices and a patient population consisting of 39 125 primary-care attendees. Diagnoses for diabetes, hypertension and co-morbidities were provided by the treating physician and complemented by blood pressure (BP) measurements and selected lab tests. Screening for microalbuminuria (>20 and <200 mu g/ml) was done with a spot urine dipstick test. Results The clinical diagnosis of nephropathy was assigned to 7.6% of patients. The point prevalence of MAU was 19.0% in the total sample; the proportion was 33.6% in diabetics whereas the diagnosis was assigned to only 71% in the total sample. Amongst diabetic patients with MAU, 92.6% had BP above the target value of <130/80 mmHg. Frequency rates rose with increasing BP (e.g. 20.6% in diabetic patients with BP<120/70 mmHg, and 36.3% in diabetic patients with BP>140/90 mmHg). Of note, patients with MAU had a higher burden of co-morbidity compared to those without MAU. Conclusions We found a high prevalence of MAU in primary care, particularly in diabetic patients. The frequency of MAU was closely related to the BP level and the degree of co-morbidity. The present study underlines the magnitude of the problem of MAU in primary care, and should serve as a starting point to initiate measures to address this important public health issue.

Item Type: Journal Article
Subjects: Q Science > QM Human anatomy
Divisions: Faculty of Medicine > Warwick Medical School
Journal or Publication Title: European Journal of Cardiovascular Prevention & Rehabilitation
Publisher: Lippincott Williams & Wilkins
ISSN: 1741-8267
Date: February 2007
Volume: Vol.14
Number: No.1
Number of Pages: 7
Page Range: pp. 107-113
Identification Number: 10.1097/01.hjr.0000224489.03221.de
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
URI: http://wrap.warwick.ac.uk/id/eprint/32351

Data sourced from Thomson Reuters' Web of Knowledge

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