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Voltage sparks a GPCR

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Stanfield, Peter (2006) Voltage sparks a GPCR. Nature, 8 (12). pp. 1323-1325. ISSN 1465-7392

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Official URL: http://dx.doi.org/10.1038/ncb1206-1323

Abstract

The response of some G-protein coupled receptors (GPRCs) is affected by the voltage across the membrane in which they sit. A study now shows that gating currents, similar to those of ion channels, are associated with this alteration in GPRC activity. The currents depend on structural elements of the receptor that functionally couple to G proteins.

Item Type: Journal Item
Subjects: Q Science > QH Natural history > QH301 Biology
Journal or Publication Title: Nature
Publisher: NATURE PUBLISHING GROUP
ISSN: 1465-7392
Date: December 2006
Volume: 8
Number: 12
Number of Pages: 4
Page Range: pp. 1323-1325
Identification Number: 10.1038/ncb1206-1323
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/32733

Data sourced from Thomson Reuters' Web of Knowledge

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