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Prostaglandin F-2 alpha increases the sensitivity of the contractile proteins to Ca2+ in human myometrium
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Woodcock, Nicola A., Taylor, Colin W. and Thornton, Steven (2006) Prostaglandin F-2 alpha increases the sensitivity of the contractile proteins to Ca2+ in human myometrium. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 195 (5). pp. 1404-1406. doi:10.1016/j.ajog.2006.03.099 ISSN 0002-9378.
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Official URL: http://dx.doi.org/10.1016/j.ajog.2006.03.099
Abstract
It is not known whether agonists (other than oxytocin) increase the contractile protein sensitivity to intracellular calcium ([Ca2+](i)) in human myometrium. We determined the calcium-tension relationship in the presence and absence of prostaglandin F-2 alpha (PGF(2 alpha)). PGF(2 alpha) increased the calcium sensitivity during both the contractile (rising) and relaxation (falling) phases of a contraction. (c) 2006 Mosby, Inc. All rights reserved.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RG Gynecology and obstetrics | ||||
Journal or Publication Title: | AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | ||||
Publisher: | MOSBY, INC | ||||
ISSN: | 0002-9378 | ||||
Official Date: | November 2006 | ||||
Dates: |
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Volume: | 195 | ||||
Number: | 5 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 1404-1406 | ||||
DOI: | 10.1016/j.ajog.2006.03.099 | ||||
Publication Status: | Published |
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