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Regulation of pancreatic beta cell function and viability by adiponectin
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Brown, J. E. P., Digby, J. E., Ward, K. L., Randeva, Harpal S. and Dunmore, S. J. (2006) Regulation of pancreatic beta cell function and viability by adiponectin. In: 42nd Annual Meeting of the European Association for the Study of Diabetes (EASD), Copenhagen, Denmark; Malmoe, Sweden, Sep 14-17, 2006. Published in: Diabetologia, Vol.49 (Suppl.1). pp. 381-382.
Full text not available from this repository.Abstract
Obesity is a risk factor for the metabolic syndrome and type 2 diabetes. Adiponectin, a 30kDa adipocyte secreted peptide has been shown to be anti-atherogenic, and anti-inflammatory, as well as affecting insulin resistance and pancreatic beta-cell function. This study investigated the effects of full length and globular adiponectin on pancreatic beta-cell viability, and expression of UCP-2, PDX-1 and LPL genes, as well as studying levels of expression of the adiponectin receptor subtypes 1 and 2 (AdR-1 and AdR-2) and their regulation in the pancreatic BRIN-BD11 beta-cell line.
| Item Type: | Conference Item (Paper) |
|---|---|
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Warwick Medical School > Biomedical Cell Biology Faculty of Medicine > Warwick Medical School |
| Journal or Publication Title: | Diabetologia |
| Publisher: | Springer |
| ISSN: | 0012-186X |
| Date: | September 2006 |
| Volume: | Vol.49 |
| Number: | Suppl.1 |
| Number of Pages: | 2 |
| Page Range: | pp. 381-382 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Funder: | European Association for the Study of Diabetes |
| Conference Paper Type: | Paper |
| Title of Event: | 42nd Annual Meeting of the European Association for the Study of Diabetes (EASD) |
| Type of Event: | Conference |
| Location of Event: | Copenhagen, Denmark; Malmoe, Sweden |
| Date(s) of Event: | Sep 14-17, 2006 |
| URI: | http://wrap.warwick.ac.uk/id/eprint/32910 |
Data sourced from Thomson Reuters' Web of Knowledge
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