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Modified Bucherer-Bergs reaction for the one-pot synthesis of 5,5 '-disubstituted hydantoins from nitriles and organometallic reagents
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Montagne, Cyril and Shipman, Michael (2006) Modified Bucherer-Bergs reaction for the one-pot synthesis of 5,5 '-disubstituted hydantoins from nitriles and organometallic reagents. Synlett (No.14). pp. 2203-2206. doi:10.1055/s-2006-949644 ISSN 0936-5214.
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Official URL: http://dx.doi.org/10.1055/s-2006-949644
Abstract
Diverse sets of 5,5'-disubstituted hydantoins can conveniently be made in moderate to good yields (40-92%) by a one-pot process involving treatment of aromatic, heteroaromatic or aliphatic nitriles with an organometallic reagent (RLi or RMgX) followed by KCN/(NH4)(2)CO3.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Journal or Publication Title: | Synlett | ||||
Publisher: | Georg Thieme Verlag | ||||
ISSN: | 0936-5214 | ||||
Official Date: | 1 September 2006 | ||||
Dates: |
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Number: | No.14 | ||||
Number of Pages: | 4 | ||||
Page Range: | pp. 2203-2206 | ||||
DOI: | 10.1055/s-2006-949644 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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