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Investigating RGS proteins in yeast

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Hill, Claire, Goddard, Alan, Davey, John and Ladds, Graham (2006) Investigating RGS proteins in yeast. Seminars in Cell & Developmental Biology, Volume 17 (Number 3). pp. 352-362. doi:10.1016/j.semcdb.2006.03.008

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Official URL: http://dx.doi.org/10.1016/j.semcdb.2006.03.008

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Abstract

Regulator of G protein signalling (RGS) proteins are vital in the adaptation of cells to stimulation via G protein-coupled receptors. Yeast have been integral in elucidating the important role that RGS proteins play within cellular processes. In addition to extensive characterisation of the endogenous RGS proteins, these organisms have enabled the identification and analysis of numerous mammalian homologues. The simplicity and plasticity of the yeast pheromone-response pathway has facilitated studies which would have been impossible in mammalian systems and it is certain that yeast will continue to have a great impact on this field of research in the future. (c) 2006 Elsevier Ltd. All rights reserved.

Item Type: Journal Item
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) > Biological Sciences ( -2010)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Journal or Publication Title: Seminars in Cell & Developmental Biology
Publisher: Elsevier Ltd
ISSN: 1084-9521
Official Date: 5 March 2006
Dates:
DateEvent
5 March 2006Available
Volume: Volume 17
Number: Number 3
Number of Pages: 11
Page Range: pp. 352-362
DOI: 10.1016/j.semcdb.2006.03.008
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

Data sourced from Thomson Reuters' Web of Knowledge

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