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The effects of diet on inflammation - Emphasis on the metabolic syndrome
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Giugliano, Dario, Ceriello, Antonio and Esposito, Katherine (2006) The effects of diet on inflammation - Emphasis on the metabolic syndrome. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 48 (4). pp. 677-685. doi:10.1016/j.jacc.2006.03.052
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Official URL: http://dx.doi.org/10.1016/j.jacc.2006.03.052
Abstract
Reducing the incidence of coronary heart disease with diet is possible. The main dietary strategies include adequate omega-3 fatty acids intake, reduction of saturated and trans-fats, and consumption of a diet high in fruits, vegetables, nuts, and whole grains and low in refined grains. Each of these strategies may be associated with lower generation of inflammation. This review examines the epidemiologic and clinical evidence concerning diet and inflammation. Dietary patterns high in refined starches, sugar, and saturated and trans-fatty acids, poor in natural antioxidants and fiber from fruits, vegetables, and whole grains, and poor in omega-3 fatty acids may cause an activation of the innate immune system, most likely by an excessive production of proinflammatory cytokines associated with a reduced production of anti-inflammatory cytokines. The whole diet approach seems particularly promising to reduce the inflammation associated with the metabolic syndrome. The choice of healthy sources of carbohydrate, fat, and protein, associated with regular physical activity and avoidance of smoking, is critical to fighting the war against chronic disease. Western dietary patterns warm up inflammation, while prudent dietary patterns cool it down.
Item Type: | Journal Item | ||||
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Subjects: | Q Science > QM Human anatomy | ||||
Journal or Publication Title: | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | ||||
Publisher: | ELSEVIER SCIENCE INC | ||||
ISSN: | 0735-1097 | ||||
Official Date: | 15 August 2006 | ||||
Dates: |
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Volume: | 48 | ||||
Number: | 4 | ||||
Number of Pages: | 9 | ||||
Page Range: | pp. 677-685 | ||||
DOI: | 10.1016/j.jacc.2006.03.052 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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