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Differential expression of mouse orexin receptor type-2 (OX2R) variants in the mouse brain

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Chen, Jing, Karteris, Emmanouil, Collins, Dawn and Randeva, Harpal S.. (2006) Differential expression of mouse orexin receptor type-2 (OX2R) variants in the mouse brain. BRAIN RESEARCH, 1103 . pp. 20-24. ISSN 0006-8993

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Official URL: http://dx.doi.org/10.1016/j.brainres.2006.05.054

Abstract

We have identified two novel mouse orexin type-2 receptor (OX2R) splice variants: OX2 alpha R and OX2 beta R. Here, we have mapped in detail the differential gene expression of OX2aR and OX2 beta R in the mouse brain. Using RT-PCR and in situ hybridization, we show that OX2aR is expressed in various areas of the mouse brain and has low expression in caudal part of cerebellum. OX2 beta R is expressed in detectable levels, with the exception of striatum, midbrain and anterior part of cerebellum/pons. Our novel findings demonstrate the differential expression of OX2R splice variants in the mouse brain. (c) 2006 Elsevier B.V. All rights reserved.

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Journal or Publication Title: BRAIN RESEARCH
Publisher: ELSEVIER SCIENCE BV
ISSN: 0006-8993
Date: 4 August 2006
Volume: 1103
Number of Pages: 5
Page Range: pp. 20-24
Identification Number: 10.1016/j.brainres.2006.05.054
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/33195

Data sourced from Thomson Reuters' Web of Knowledge

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