A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot
Wassink, Geert J., King, Elisabeth M., Grogono-Thomas, Rosemary, Brown, J. C., Moore, Lynda J. and Green, Laura E.. (2010) A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot. Preventive Veterinary Medicine, Vol.96 (No.1-2). pp. 93-103. ISSN 0167-5877
WRAP_Green_A_clinical_trial_of_two_treatments_Green_-_PMVrevision_WRAP.pdf - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Official URL: http://dx.doi.org/10.1016/j.prevetmed.2010.05.006
From observational studies, farmers who use parenteral antibacterials to promptly treat all sheep with footrot (FR) or interdigital dermatitis (ID) have a prevalence of lameness of <2% compared with a prevalence of 9% lameness reported by farmers who treat lame sheep by trimming affected feet. We tested the hypothesis that prompt treatment of sheep lame with naturally developing FR or ID with parenteral and topical antibacterials reduces the prevalence and incidence of lameness with these conditions compared with less frequent treatment with trimming of hoof horn and applying topical antibacterials. A further hypothesis was that reduction of ID and FR would improve productivity. A lowland sheep flock with 700 ewes was used to test these hypotheses in an 18-month within farm clinical trial with four groups of ewes: two intervention and two control. The duration and severity of lameness was used to categorise sheep into three weighted scores of lameness (WLS): never lame (WLS0), mildly lame/lame for <6 days (WLS1) and severely or chronically lame (WLS2). The intervention reduced the prevalence of lameness due to FR and ID in ewes and lambs and the incidence of lameness in ewes. The WLS was also significantly lower in sheep in the intervention groups. Ewes with a higher WLS were subsequently significantly more likely to have a body condition score <2.5 and to have lame lambs. Significantly more ewes lambed and successfully reared more lambs that were ready for slaughter at a younger age in the intervention versus control groups. There was an increase in the gross margin of £630/100 ewes mated in the intervention group, including the cost of treatment of £150/100 ewes mated. We conclude that prompt parenteral and topical antibacterial treatment of sheep lame with ID and FR reduced the prevalence and incidence of these infectious conditions and led to improved health, welfare and productivity.
|Item Type:||Journal Article|
|Subjects:||S Agriculture > SF Animal culture
Q Science > QL Zoology
|Divisions:||Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)|
|Library of Congress Subject Headings (LCSH):||Footrot in sheep -- Treatment, Lameness in sheep -- Treatment, Antibiotics in veterinary medicine|
|Journal or Publication Title:||Preventive Veterinary Medicine|
|Official Date:||August 2010|
|Page Range:||pp. 93-103|
|Access rights to Published version:||Open Access|
|Funder:||Great Britain. Dept. for Environment, Food & Rural Affairs (DEFRA)|
|Grant number:||AW1021 (DEFRA)|
Abecia et al., 2006 J.A. Abecia, C. Sosa, F. Forcada and A. Meikle, The effect of undernutrition on the establishment of pregnancy in the ewe, Reprod. Nutr. Dev. 46 (2006), pp. 367–378. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (15)
Beveridge, 1941 Beveridge, W.I.B., 1941. Foot rot in sheep: a transmissible disease due to infection with Fusiformis nodosus (n. sp.): studies on its cause, epidemiology and control., Australian Bulletin. Commonwealth Scientific and Industrial Research Organisation (CSIRO). pp. 1–56.
Binns et al., 2002 S.H. Binns, I.J. Cox, S. Rizvi and L.E. Green, Risk factors for lamb mortality on UK sheep farms, Prev. Vet. Med. 52 (2002), pp. 287–303. Article | PDF (173 K) | View Record in Scopus | Cited By in Scopus (24)
Christley et al., 2003 R.M. Christley, K.L. Morgan, T.D.H. Parkin and N.P. French, Factors related to the risk of neonatal mortality, birth-weight and serum immunoglobulin concentration in lambs in the UK, Prev. Vet. Med. 57 (2003), pp. 209–226. Article | PDF (183 K) | View Record in Scopus | Cited By in Scopus (20)
DEFRA, 2008 DEFRA, 2008. An intervention study to minimise footrot in sheep. Final report AW1021.
Depiazzi et al., 1991 L.J. Depiazzi, R.B. Richards, J. Henderson, J.I. Rood, M. Palmer and W.J. Penhale, Characterisation of virulent and benign strains of Bacteroides nodosus, Vet. Microbiol. 26 (1991), pp. 151–160. Abstract | PDF (681 K) | View Record in Scopus | Cited By in Scopus (13)
Egerton et al., 1968 J.R. Egerton, I.M. Parsonson and N.P.H. Graham, Parenteral chemotherapy of ovine footrot, Aust. Vet. J. 44 (1968), pp. 275–282.
Everett-Hincks and Dodds, 2008 J.M. Everett-Hincks and K.G. Dodds, Management of maternal-offspring behavior to improve lamb survival in easy care sheep systems, J. Anim. Sci. 86 (2008), pp. E259–E270.
Fitzpatrick et al., 2006 J. Fitzpatrick, M. Scott and A. Nolan, Assessment of pain and welfare in sheep, Small Rumin. Res. 62 (2006), pp. 55–61. Article | PDF (98 K) | View Record in Scopus | Cited By in Scopus (16)
Forcada et al., 1992 F. Forcada, J.A. Abecia and I. Sierra, Seasonal changes in oestrus activity and ovulation rate in Rasa Aragonesa ewes maintained at two different body condition levels, Small Rumin. Res. 8 (1992), pp. 313–324. Article | PDF (749 K) | View Record in Scopus | Cited By in Scopus (42)
Goddard et al., 2006 P. Goddard, T. Waterhouse, C. Dwyer and A. Stott, The perception of welfare sheep in extensive systems, Small Rumin. Res. 62 (2006), pp. 215–225. Article | PDF (285 K) | View Record in Scopus | Cited By in Scopus (8)
Goldstein, 2003 H. Goldstein, Multilevel Statistical Models, Arnold London (2003).
Green and George, 2007 L.E. Green and T.R.N. George, Assessment of current knowledge of footrot in sheep with particular reference to Dichelobacter nodosus and implications for elimination or control strategies for sheep in Great Britain, Vet. J. 175 (2) (2007), pp. 173–180.
Green et al., 2007 L.E. Green, G.J. Wassink, R. Grogono-Thomas, L.J. Moore and G.F. Medley, Looking after the individual to reduce disease in the flock: a binomial mixed effects model investigating the impact of individual sheep management of footrot and interdigital dermatitis in a prospective longitudinal study on one farm, Prev. Vet. Med. 78 (2007), pp. 172–178. Article | PDF (193 K) | View Record in Scopus | Cited By in Scopus (10)
Grogono-Thomas and Johnston, 1997 Grogono-Thomas, R., Johnston, K.M., 1997. A study of ovine lameness. MAFF open contract OC59 45K. MAFF Final Report. MAFF, London.
Grogono-Thomas et al., 1994 R. Grogono-Thomas, A.J. Wilsmore, A.J. Simon and K.A. Izzard, The use of long-acting oxytetracycline for the treatment of ovine footrot, Br. Vet. J. 150 (1994), pp. 561–568. Abstract | PDF (344 K) | View Record in Scopus | Cited By in Scopus (8)
Hawker, 2008 Hawker EM, (2008) An intervention study to minimise lameness in sheep. MSc thesis. University of Warwick, UK.
Kaler and Green, 2008 J. Kaler and L.E. Green, Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers, Prev. Vet. Med. 83 (2008), pp. 52–64. Article | PDF (358 K) | View Record in Scopus | Cited By in Scopus (8)
Kaler et al., 2008 J. Kaler, G.J. Wassink and L.E. Green, The inter- and intra-observer reliability of a locomotion scoring scale for sheep, Vet. J. 180 (2008), pp. 189–194.
Kaler and Green, 2009 J. Kaler and L.E. Green, Farmers’ practices and factors associated with the prevalence of all lameness and lameness attributed to interdigital dermatitis and footrot in sheep flocks in England in 2004, Prev. Vet. Med. (2009) 10.1016/j.prevetmed.2009.08.001.
Kaler et al., 2010 J. Kaler, S.L.S. Daniels, J.W. Wright and L.E. Green, A randomised factorial design clinical trial to investigate the impact of parenteral long acting oxytetracycline, foot trimming and flunixine meglumine on time to recovery from lameness with footrot in sheep, J. Vet. Intern. Med. (2010) 10.1111/j.1939-1676.2009.0450.x.
MAFF, 1994 MAFF, 1994. Condition scoring of sheep. Action on Animal Welfare. Pamphlet PB187.
Marshall et al., 1991 D.J. Marshall, R.I. Walker, B.R. Cullis and M.F. Luff, The effect of footrot on body weight and wool growth of sheep, Aust. Vet. J. 68 (1991), pp. 45–49. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (18)
Mellor and Murray, 1985 D.J. Mellor and L. Murray, Effects of maternal nutrition on udder development during late pregnancy and on colostrum production in Scottish Blackface ewes with twin lambs, Res. Vet. Sci. 39 (1985), pp. 230–234. View Record in Scopus | Cited By in Scopus (29)
MLC, 2007 MLC, UK Yearbook 2007 meat and livestock, Economics, Meat and Livestock Commission, Milton Keynes (2007).
Moore et al., 2005 L.J. Moore, G.J. Wassink, L.E. Green and R. Grogono-Thomas, The detection and characterisation of Dichelobacter nodosus from cases of ovine footrot in England and Wales, Vet. Microbiol. 108 (2005), pp. 57–67. Article | PDF (196 K) | View Record in Scopus | Cited By in Scopus (14)
Nieuwhof et al., 2008 G. Nieuwhof, S.C. Bishop, W.G. Hill and H.W. Raadsma, The effect of footrot on weight gain in sheep, Anim. 2 (2008), pp. 1427–1436. View Record in Scopus | Cited By in Scopus (2)
Nieuwhof and Bishop, 2005 G. Nieuwhof and S.C. Bishop, Costs of the major endemic diseases of sheep in Great Britain and the potential benefits of reduction in disease impacts, Anim. Sci. 81 (2005), pp. 57–67.
O’Doherty et al., 1997 J.V. O’Doherty, P.F. Maher and T.F. Crosby, The performance of pregnant ewes and their progeny when offered grass silage, maize silage or a maize silage/ensiled super pressed pulp mixture during late pregnancy, Livest. Prod. Sci. 52 (1997), pp. 11–19.
Rasbash et al., 1999 J. Rasbash, W. Browne, M. Healy, B. Cameron and C. Charlton, MLwiN Beta version 01.10.0001 (1999).
Rhind and McNeilly, 1986 S.M. Rhind and A.S. McNeilly, Follicle populations, ovulation rates and plasma profiles of LH, FSH and prolactin in Scottish Blackface ewes in high and low levels of body condition, Anim. Reprod. Sci. 10 (1986), pp. 105–115. Article | PDF (623 K) | View Record in Scopus | Cited By in Scopus (18)
Schwartzkoff et al., 1993 C.L. Schwartzkoff, J.R. Egerton, D.J. Stewart, P.R. Lehrbach, T.C. Elleman and P.A. Hoyne, The effects of antigenic competition on the efficacy of multivalent FR vaccines, Aust. Vet. J. 70 (1993), pp. 123–126. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (17)
Sterk, 1960 V. Sterk, A contribution to the parenteral application of the remedies for the treatment of footrot in sheep, Vet. Sarajevo 9 (1960), pp. 277–281.
Stewart et al., 1984 D.J. Stewart, B.L. Clark and R.G. Jarrett, Differences between strains of Bacteroides nodosus in their effects on the severity of foot-rot, bodyweight and wool growth in Merino sheep, Aust. Vet. J. 61 (1984), pp. 348–352. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (13)
Wassink et al., 2003 G.J. Wassink, R. Grogono-Thomas, L.J. Moore and L.E. Green, Risk factors associated with the prevalence of footrot in sheep from 1999 to 2000, Vet. Rec. 152 (2003), pp. 351–358. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (21)
Wassink et al., 2005 G.J. Wassink, L.J. Moore, R. Grogono-Thomas and L.E. Green, Footrot and interdigital dermatitis in sheep: farmers practices, opinions and attitudes, Vet. Rec. 157 (2005), pp. 761–765.
Williams, 2000 R.L. Williams, A note on robust variance estimation for cluster-correlated data, Biometrics 56 (2000), pp. 645–646. View Record in Scopus | Cited By in Scopus (487)
Winter, 2004 A.C. Winter, Lameness in Sheep, Crowood Press, Marlborough, UK (2004).
Actions (login required)