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Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period
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Tooher, Rebecca, Gates, Simon, Dowswell, Therese and Davis, Lucy-Jane (2010) Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period. Cochrane Database of Systematic Reviews (No.5). Article CD001689. doi:10.1002/14651858.CD001689.pub2
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Official URL: http://dx.doi.org/10.1002/14651858.CD001689.pub2
Abstract
Some women are at risk of forming blood clots in a deep vein during pregnancy, after a caesarean birth, or during the first few weeks after childbirth. If part of the clot breaks off and lodges in a blood vessel in the lungs, it can be life-threatening. Preventive treatments include blood-thinning drugs to prevent clots, support stockings, and exercise soon after the birth to keep circulation moving. However, some drugs might cause problems such as increased blood loss after the birth. Drugs used include heparin, low molecular weight heparin and aspirin. We included 16 randomised controlled studies in the review but only 13 trials with 1774 women contributed data for the outcomes of interest. We did not find enough evidence from the trials to be sure about the effects of these different preventive treatments.This means there is not enough evidence to show which are the best ways to prevent deep vein thrombosis (DVT) during or following pregnancy, or after a caesarean birth.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RG Gynecology and obstetrics | ||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Thromboembolism, Mothers -- Mortality, Pregnancy -- Complications, Obstetrical pharmacology | ||||
| Journal or Publication Title: | Cochrane Database of Systematic Reviews | ||||
| Publisher: | John Wiley & Sons Ltd. | ||||
| ISSN: | 1469-493X | ||||
| Official Date: | 2010 | ||||
| Dates: |
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| Number: | No.5 | ||||
| Page Range: | Article CD001689 | ||||
| DOI: | 10.1002/14651858.CD001689.pub2 | ||||
| Status: | Peer Reviewed | ||||
| Access rights to Published version: | Open Access | ||||
| Funder: | University of Liverpool, National Institute for Health Research (Great Britain) (NIHR) | ||||
| Grant number: | CPGS02 (NIHR) |
Data sourced from Thomson Reuters' Web of Knowledge
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