Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus

Tools
- Tools
+ Tools

UNSPECIFIED (2006) Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus. DIABETOLOGIA, 49 (5). pp. 846-854. doi:10.1007/s00125-006-0203-x

Full text not available from this repository, contact author.
Official URL: http://dx.doi.org/10.1007/s00125-006-0203-x

Request Changes to record.

Abstract

Post-prandial glucose may be a risk factor for cardiovascular disease and chronic diabetic complications. We tested the hypothesis that post-prandial hyperglycaemia is common in type 2 diabetes, even among patients in apparently good glycaemic control, and that simple clinical characteristics identify subsets of diabetic patients with frequent post-prandial hyperglycaemia.

Three self-assessed daily blood glucose profiles over a 1-week period, including 18 glucose readings before and 2 h after meals, were obtained from 3,284 unselected outpatients (men 51%; age 63 +/- 10 years) with non-insulin-treated type 2 diabetes mellitus attending 500 different diabetes clinics operating throughout Italy.

A post-prandial blood glucose value > 8.89 mmol/l (160 mg/dl) was recorded at least once in 84% of patients, and 81% of patients had at least one Delta glucose >= 2.22 mmol/l (40 mg/dl). Among patients with apparently good metabolic control, 38% had > 40% of post-prandial blood glucose readings > 8.89 mmol/l (>= 4 of 9 meals in total), and 36% had > 40% Delta glucose >= 2.22 mmol/l. In multivariate analysis adjusted for pre-prandial glucose levels, older age, longer duration of diabetes, absence of obesity, hyperlipidaemia and hypertension, as well as treatment with sulfonylureas, were significantly associated with greater glucose excursions after meals.

These results indicate that post-prandial hyperglycaemia is a very frequent phenomenon in patients with type 2 diabetes mellitus on active treatment; can occur even when metabolic control is apparently good; and can be predicted by simple clinical features.

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine
Journal or Publication Title: DIABETOLOGIA
Publisher: SPRINGER
ISSN: 0012-186X
Official Date: May 2006
Dates:
DateEvent
May 2006UNSPECIFIED
Volume: 49
Number: 5
Number of Pages: 9
Page Range: pp. 846-854
DOI: 10.1007/s00125-006-0203-x
Publication Status: Published

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item
twitter

Email us: publications@live.warwick.ac.uk
Contact Details
About Us