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Total and relative deficiency of gut mucosal IgA In German shepherd dogs demonstrated by faecal analysis

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UNSPECIFIED (2006) Total and relative deficiency of gut mucosal IgA In German shepherd dogs demonstrated by faecal analysis. VETERINARY RECORD, 158 (10). pp. 334-341. ISSN 0042-4900

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Abstract

The concentration of immunoglobulins in faecal extracts was investigated as a method of assessing the production of immunoglobulins by the gut mucosa of 137 dogs. There were significant correlations between the concentrations in faecal extracts and the concentrations produced in duodenal organ cultures. Seventy-six German shepherd dogs had significantly lower median immunoglobulin A (IgA) concentrations in their faecal extracts than 63 controls of various breeds. Sixteen of the German shepherd dogs had IgA concentrations below the 95 per cent confidence limit of the control population and six had no demonstrable faecal IgA. The faecal concentrations of immunoglobulin G and albumin were significantly higher in the German shepherd dogs than in the controls, but their immunoglobulin M concentrations were similar.

Item Type: Journal Article
Subjects: S Agriculture > SF Animal culture
Journal or Publication Title: VETERINARY RECORD
Publisher: BRITISH VETERINARY ASSOC
ISSN: 0042-4900
Date: 11 March 2006
Volume: 158
Number: 10
Number of Pages: 8
Page Range: pp. 334-341
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/33735

Data sourced from Thomson Reuters' Web of Knowledge

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