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Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites
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Walton, Laura J., Corre, Christophe and Challis, Gregory L. (2006) Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites. In: Joint 8th Symposium on the Genetics and Molecular Biology of Industrial Microorganisms/8th International Conference on Biotechnology of Microbial Products, San Diego, USA, 14-18 Vov2004. Published in: Journal of Industrial Microbiology and Biotechnology, Volume 33 (Number 2). pp. 105-120. doi:10.1007/s10295-005-0026-7 ISSN 1367-5435.
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Official URL: http://dx.doi.org/10.1007/s10295-005-0026-7
Abstract
Several polyketide secondary metabolites are shown by feeding experiments to incorporate glycerol-derived 3-carbon starter units, 2-carbon extender units, or 3-carbon branches into their hydrocarbon chains. In recent years, genetic studies have begun to elucidate the mechanisms by which this occurs. In this article we review the incorporation of glycerol-derived precursors into polyketides and propose new mechanisms for the incorporation processes.
| Item Type: | Conference Item (Paper) | ||||
|---|---|---|---|---|---|
| Subjects: | T Technology > TP Chemical technology | ||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) |
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| Journal or Publication Title: | Journal of Industrial Microbiology and Biotechnology | ||||
| Publisher: | Springer | ||||
| ISSN: | 1367-5435 | ||||
| Official Date: | February 2006 | ||||
| Dates: |
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| Volume: | Volume 33 | ||||
| Number: | Number 2 | ||||
| Number of Pages: | 16 | ||||
| Page Range: | pp. 105-120 | ||||
| DOI: | 10.1007/s10295-005-0026-7 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Conference Paper Type: | Paper | ||||
| Title of Event: | Joint 8th Symposium on the Genetics and Molecular Biology of Industrial Microorganisms/8th International Conference on Biotechnology of Microbial Products | ||||
| Type of Event: | Conference | ||||
| Location of Event: | San Diego, USA | ||||
| Date(s) of Event: | 14-18 Vov2004 |
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