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Rapid accurate mass desorption electrospray ionisation tandem mass spectrometry of pharmaceutical samples
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UNSPECIFIED (2005) Rapid accurate mass desorption electrospray ionisation tandem mass spectrometry of pharmaceutical samples. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 19 (24). pp. 3643-3650. doi:10.1002/rcm.2251 ISSN 0951-4198.
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Official URL: http://dx.doi.org/10.1002/rcm.2251
Abstract
Desorption electrospray ionisation (DESI) has been successfully combined with a hybrid quadrupole time-of-flight mass spectrometer to provide mass spectra and product ion mass spectra of active ingredients formulated in pharmaceutical tablets, gels and ointments. Accurate mass data has been obtained from the DESI mass spectra and of the product ion fragments of selected ions, greatly enhancing the selectivity and information content of the experiment. This accurate mass information only takes seconds to acquire since the DESI technique does not require any sample preparation or extraction prior to mass analysis. Copyright (c) 2005 John Wiley & Sons, Ltd.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QC Physics |
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| Journal or Publication Title: | RAPID COMMUNICATIONS IN MASS SPECTROMETRY | ||||
| Publisher: | JOHN WILEY & SONS LTD | ||||
| ISSN: | 0951-4198 | ||||
| Official Date: | 2005 | ||||
| Dates: |
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| Volume: | 19 | ||||
| Number: | 24 | ||||
| Number of Pages: | 8 | ||||
| Page Range: | pp. 3643-3650 | ||||
| DOI: | 10.1002/rcm.2251 | ||||
| Publication Status: | Published |
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