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Four unusual two-component signal transduction homologs, RedC to RedF, are necessary for timely development in Myxococcus xanthus
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UNSPECIFIED. (2005) Four unusual two-component signal transduction homologs, RedC to RedF, are necessary for timely development in Myxococcus xanthus. JOURNAL OF BACTERIOLOGY, 187 (23). pp. 8191-8195. ISSN 0021-9193
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Official URL: http://dx.doi.org/10.1128/JB.187.23.8191-8195.2005
Abstract
We identified a cluster of four two-component signal transduction genes that are necessary for proper progression of Myxococcus xanthus through development. redC to redF mutants developed and sporulated early, resulting in small, numerous, and disorganized fruiting bodies. Yeast two-hybrid analyses suggest that RedCDEF act in a single signaling pathway. The previously identified espA gene displays a phenotype similar to that of redCDEF. However, combined mutants defective in espA redCDEF exhibited a striking additive developmental phenotype, suggesting that EspA and RedC to RedF play independent roles in controlling developmental progression.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QR Microbiology |
| Journal or Publication Title: | JOURNAL OF BACTERIOLOGY |
| Publisher: | AMER SOC MICROBIOLOGY |
| ISSN: | 0021-9193 |
| Date: | December 2005 |
| Volume: | 187 |
| Number: | 23 |
| Number of Pages: | 5 |
| Page Range: | pp. 8191-8195 |
| Identification Number: | 10.1128/JB.187.23.8191-8195.2005 |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/34106 |
Data sourced from Thomson Reuters' Web of Knowledge
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