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Ricin: current understanding and prospects for an antiricin vaccine
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UNSPECIFIED (2005) Ricin: current understanding and prospects for an antiricin vaccine. EXPERT REVIEW OF VACCINES, 4 (2). pp. 229-237. doi:10.1586/14760584.4.2.229
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Official URL: http://dx.doi.org/10.1586/14760584.4.2.229
Abstract
Ricin is a potent cytotoxin that can be rapidly internalized into mammalian cells leading to cell death. The ease in obtaining the toxin and its deadly nature combine to implicate ricin as a convenient agent for bioterrorism. Research into the mechanism of toxicity, as well as strategies for treatment and protection from the toxin has been widely undertaken for a number of years. This article reviews the current understanding of the mechanism of action of the toxin, the clinical effects of ricin intoxication and how these relate to current and continuing prospects for vaccine development.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QR Microbiology > QR180 Immunology | ||||
| Journal or Publication Title: | EXPERT REVIEW OF VACCINES | ||||
| Publisher: | FUTURE DRUGS LTD | ||||
| ISSN: | 1476-0584 | ||||
| Official Date: | April 2005 | ||||
| Dates: |
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| Volume: | 4 | ||||
| Number: | 2 | ||||
| Number of Pages: | 9 | ||||
| Page Range: | pp. 229-237 | ||||
| DOI: | 10.1586/14760584.4.2.229 | ||||
| Publication Status: | Published |
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