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Ricin: current understanding and prospects for an antiricin vaccine

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UNSPECIFIED (2005) Ricin: current understanding and prospects for an antiricin vaccine. EXPERT REVIEW OF VACCINES, 4 (2). pp. 229-237. doi:10.1586/14760584.4.2.229

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Official URL: http://dx.doi.org/10.1586/14760584.4.2.229

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Abstract

Ricin is a potent cytotoxin that can be rapidly internalized into mammalian cells leading to cell death. The ease in obtaining the toxin and its deadly nature combine to implicate ricin as a convenient agent for bioterrorism. Research into the mechanism of toxicity, as well as strategies for treatment and protection from the toxin has been widely undertaken for a number of years. This article reviews the current understanding of the mechanism of action of the toxin, the clinical effects of ricin intoxication and how these relate to current and continuing prospects for vaccine development.

Item Type: Journal Item
Subjects: Q Science > QR Microbiology > QR180 Immunology
Journal or Publication Title: EXPERT REVIEW OF VACCINES
Publisher: FUTURE DRUGS LTD
ISSN: 1476-0584
Official Date: April 2005
Dates:
DateEvent
April 2005UNSPECIFIED
Volume: 4
Number: 2
Number of Pages: 9
Page Range: pp. 229-237
DOI: 10.1586/14760584.4.2.229
Publication Status: Published

Data sourced from Thomson Reuters' Web of Knowledge

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