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Outcome selection bias in meta-analysis

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UNSPECIFIED (2005) Outcome selection bias in meta-analysis. STATISTICAL METHODS IN MEDICAL RESEARCH, 14 (5). pp. 515-524. ISSN 0962-2802

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Official URL: http://dx.doi.org/10.1191/0962280205sm415oa

Abstract

Publication bias has been previously identified as a threat to the validity of a meta-analysis. Recently, new evidence has documented an additional threat to validity, the selective reporting of trial outcomes within published studies. Several diseases have several possible measures of outcome. Some articles might report only a selection of those outcomes, perhaps those with statistically significant results. In this article, we review this problem while addressing the questions: what is within-study selective reporting? how common is it? why is it done? how can it mislead? how can it be detected?, and finally, what is the solution? We recommend that both publication bias and selective reporting should be routinely investigated in systematic reviews.

Item Type: Journal Item
Subjects: H Social Sciences > HV Social pathology. Social and public welfare
Q Science > QH Natural history > QH301 Biology
R Medicine
Q Science > QA Mathematics
Journal or Publication Title: STATISTICAL METHODS IN MEDICAL RESEARCH
Publisher: HODDER ARNOLD, HODDER HEADLINE PLC
ISSN: 0962-2802
Date: October 2005
Volume: 14
Number: 5
Number of Pages: 10
Page Range: pp. 515-524
Identification Number: 10.1191/0962280205sm415oa
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/34449

Data sourced from Thomson Reuters' Web of Knowledge

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