Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors : discrimination between various base-pair mismatches
Duprey, Jean-Louis, Bassani, Dario, Hyde, Eva, Ludwig, Christian, Rodger, Alison, Vyle, Joseph, Wilkie, John, Zhao, Zheng-Yun and Tucker, James. (2011) Anthracene-modified oligonucleotides as fluorescent DNA mismatch sensors : discrimination between various base-pair mismatches. Supramolecular Chemistry, Vol.23 (No.3-4). pp. 273-277. ISSN 1061-0278Full text not available from this repository.
Official URL: http://dx.doi.org/10.1080/10610278.2010.523117
A fluorescent anthracene-tagged DNA probe has been shown to respond to various DNA sequences by changes to its emission signal upon duplex formation. The fluorescence response for duplexes containing a single mismatch near the anthracene site has been found to be very sensitive to its composition, with the emission signal increasing for a CA mismatch and decreasing for CT and CC mismatches.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry
Q Science > QH Natural history > QH426 Genetics
Q Science > QP Physiology
|Divisions:||Faculty of Science > Chemistry|
|Library of Congress Subject Headings (LCSH):||Anthracene, Fluorimetry, Fluorescent probes, DNA, Nucleotide sequence, Oligonucleotides|
|Journal or Publication Title:||Supramolecular Chemistry|
|Publisher:||Taylor & Francis Ltd.|
|Page Range:||pp. 273-277|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||University of Birmingham, Engineering and Physical Sciences Research Council (EPSRC), Advantage West Midlands|
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