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Electronic transport in DNA

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Klotsa, Daphne, Roemer, Rudolf A. and Turner, Mathew S. . (2008) Electronic transport in DNA. Biophysical Journal, Vol.89 . pp. 2187-2198. ISSN 0006-3495

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Official URL: http://dx.doi.org/10.1529/biophysj.105.064014

Abstract

We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localization lengths (crudely speaking, the length over which electrons travel). Various types of disorder, including random potentials, are employed to account for different real environments. We have performed calculations on poly(dG)-poly(dC), telomeric-DNA, random-ATGC DNA, and l-DNA. We find that random and l-DNA have localization lengths allowing for electron motion among a few dozen basepairs only. A novel enhancement of localization lengths is observed at particular energies for an increasing binary backbone disorder. We comment on the possible biological relevance of sequence-dependent charge transfer in DNA.

Item Type:	Journal Article
Subjects:	Q Science > QC Physics
Divisions:	Faculty of Science > Centre for Scientific Computing Faculty of Science > Physics
Library of Congress Subject Headings (LCSH):	DNA, Charge transfer in biology
Journal or Publication Title:	Biophysical Journal
Publisher:	Biophysical Society
ISSN:	0006-3495
Date:	29 October 2008
Volume:	Vol.89
Page Range:	pp. 2187-2198
Identification Number:	10.1529/biophysj.105.064014
Status:	Peer Reviewed
Access rights to Published version:	Open Access
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URI:	http://wrap.warwick.ac.uk/id/eprint/351