Bell, David J., Wootton, Daniel G., Mukaka, Mavuto, Montgomery, Jacqui, Kayange, Noel, Chimpeni, Phillips, Hughes, Dyfrig, Molyneux, Malcolm E., Ward, Steve A., Winstanley, Peter and Lalloo, David G. (2009) Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. Malaria Journal, Vol.8 (No.204). doi:10.1186/1475-2875-8-204

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Abstract

Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance. At the time of this study, artemether-lumefantrine (AL) and chlorproguanil-dapsone (CPD), both multi-dose regimes, were considered possible alternatives to SP in Malawi. The aim of this study was to investigate the impact of poor adherence on the effectiveness of AL and CPD.

Item Type:	Journal Article
Subjects:	R Medicine > RA Public aspects of medicine
Divisions:	Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Malaria -- Treatment -- Malawi
Journal or Publication Title:	Malaria Journal
Publisher:	BioMed Central Ltd.
ISSN:	1475-2875
Official Date:	29 August 2009
Dates:	Date Event 29 August 2009 Published
Date of first compliant deposit:	17 December 2015
Volume:	Vol.8
Number:	No.204
DOI:	10.1186/1475-2875-8-204
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Funder:	Great Britain. Dept. for International Development
Grant number:	RES 8074 (DID)

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