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Multimodal functional imaging investigation before and after the onset of psychosis
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Fusar-Poli, Paolo, Howes, Oliver (Oliver D.), Valli, Isabel, Allen, Paul, Broome, Matthew R., Grasby, Paul and McGuire, Philip. (2009) Multimodal functional imaging investigation before and after the onset of psychosis. International Journal of Neuropsychopharmacology, Vol.12 (No.4). pp. 579-581. ISSN 1461-1457
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Official URL: http://dx.doi.org/10.1017/S146114570800953X
Abstract
Mr A. was a 20-yr-old white male with no medical history of note. His GP, who was concerned about his poor psychosocial functioning, referred him to a specialist service offering advice and support for young people at risk for psychosis.
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing Faculty of Medicine > Warwick Medical School |
| Library of Congress Subject Headings (LCSH): | Schizophrenia -- Physiological aspects, Diagnostic imaging |
| Journal or Publication Title: | International Journal of Neuropsychopharmacology |
| Publisher: | Cambridge University Press |
| ISSN: | 1461-1457 |
| Date: | 2009 |
| Volume: | Vol.12 |
| Number: | No.4 |
| Page Range: | pp. 579-581 |
| Identification Number: | 10.1017/S146114570800953X |
| Status: | Peer Reviewed |
| Access rights to Published version: | Open Access |
| References: | Cropley VL, Fujita M, Innis RB, Nathan PJ (2006). Molecular imaging of the dopaminergic system and its association with human cognitive function. Biological Psychiatry 59, 898–907. Floresco SB, Magyar O (2006). Mesocortical dopamine modulation of executive functions: beyond working memory. Psychopharmacology 188, 567–585. Fusar Poli P, Perez J, Broome M, Borgwardt S, Placentino A (2007). Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews 31, 465–484. Grunder G, Vernaleken I, Muller MJ, Davids E, Heydari N, Buchholz HG (2003). Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo. Neuropsychopharmacology 28, 787–794. Howes OD, Montgomery AJ, Asselin MC, Murray RM, Valli I, Grasby P (in press). Elevated striatal dopamine function linked to prodromal signs of schizophrenia. Archives of General Psychiatry. McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T (2006). Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. American Journal of Psychiatry 163, 790–799. McGorry PD, Yung AR, Phillips LJ, Yuen HP, Francey S (2002). Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. Archives of General Psychiatry 59, 921–928. McGowan S, Lawrence AD, Sales T, Quested D, Grasby P (2004). Presynaptic dopaminergic dysfunction in schizophrenia: a positron emission tomographic [18F]fluorodopa study. Archives of General Psychiatry 61, 134–142. McGuire P, Howes OD, Stone J, Fusar-Poli P (2008). Functional neuroimaging in schizophrenia: diagnosis and drug discovery. Trends in Pharmacological Science 29, 91–98. Tanaka S (2006). Dopaminergic control of working memory and its relevance to schizophrenia: a circuit dynamics perspective. Neuroscience 139, 153–171. Vernaleken I, Kumakura Y, Cumming P, Buchholz HG, Siessmeier T, Stoeter P (2006). Modulation of [18F]fluorodopa (FDOPA) kinetics in the brain of healthy volunteers after acute haloperidol challenge. Neuroimage 30, 1332–1339. Weinhard K (1998). The Theory and Practice of 3D PET. In: Bendriem B, Townsend DW(Eds), pp. 150–154. Dordrecht : Kluwer Academic Publishers. Yung A, Phillips L, McGorry P, Ward J, Donovan K (2002). Comprehensive Assessment of At Risk Mental States (CAARMS). Melbourne: PACE Clinic, Department of Psychiatry, University of Melbourne. Yung AR, Phillips LJ, Yuen HP, Francey SM,McFarlane CA (2003). Psychosis prediction: 12-month follow up of a high-risk (‘prodromal’) group. Schizophrenia Research 60, 21–32. |
| URI: | http://wrap.warwick.ac.uk/id/eprint/36492 |
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