Organocatalytic synthesis of astaxanthin-containing poly(lactide)s
Middleton, Helen, Tempelaar, Sarah, Haddleton, David M. and Dove, Andrew P.. (2011) Organocatalytic synthesis of astaxanthin-containing poly(lactide)s. Polymer Chemistry, Vol.2 (No.3). pp. 595-600. ISSN 1759-9954Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/C0PY00227E
The synthesis of astaxanthin-containing poly(lactide)s is reported by the ring-opening polymerization of lactide initiated from residual alcohol groups on astaxanthin using a previously reported thiourea/tertiary amine catalyst. Polymers with molecular weights between 2500 and 30000 g mol−1 are obtained with excellent levels of control, astaxanthin incorporation being confirmed by UV/Vis detected GPC, 1H NMR, MALDI-TOF MS and IR spectroscopic analysis. Study of the polymerizations at extended time periods revealed greatly increased levels of transesterification in comparison to polymerizations initiated by 4-pyrene-1-butanol, attributed to increased intramolecular transesterification side reactions.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Divisions:||Faculty of Science > Chemistry|
|Library of Congress Subject Headings (LCSH):||Polymerization, Ring formation (Chemistry), Organic compounds -- Synthesis, Transesterification, Bioconjugates|
|Journal or Publication Title:||Polymer Chemistry|
|Publisher:||Royal Society of Chemistry|
|Official Date:||March 2011|
|Page Range:||pp. 595-600|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||Research Councils UK (RCUK), Engineering and Physical Sciences Research Council (EPSRC), Warwick Effect Polymers Ltd.|
|Grant number:||EP/C007999/1 (EPSRC)|
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