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Tunable thermo-responsive polymer–protein conjugates via a combination of nucleophilic thiol–ene “click” and SET-LRP
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Jones, Mathew W., Gibson, Matthew I., Mantovani, Giuseppe and Haddleton, David M.. (2011) Tunable thermo-responsive polymer–protein conjugates via a combination of nucleophilic thiol–ene “click” and SET-LRP. Polymer Chemistry, Vol.2 (No.3). pp. 572-574. ISSN 1759-9954
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Official URL: http://dx.doi.org/10.1039/C0PY00329H
Abstract
Herein we report the synthesis of a protein macroinitiator in a one-pot strategy using phosphine-mediated thiol–ene “click”, the macroinitiator was used to polymerise ethylene glycol containing monomers to yield polymer–protein conjugates with tunable thermoresponsive behaviour.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Chemistry |
| Library of Congress Subject Headings (LCSH): | Polymerization, Organic compounds -- Synthesis, Bioconjugates, Nucleophilic reactions, Conjugated polymers |
| Journal or Publication Title: | Polymer Chemistry |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1759-9954 |
| Date: | March 2011 |
| Volume: | Vol.2 |
| Number: | No.3 |
| Page Range: | pp. 572-574 |
| Identification Number: | 10.1039/c0py00329h |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Funder: | Engineering and Physical Sciences Research Council (EPSRC), Warwick Effect Polymers Ltd, European Regional Development Fund (ERDF), HEFCE |
| URI: | http://wrap.warwick.ac.uk/id/eprint/36950 |
Data sourced from Thomson Reuters' Web of Knowledge
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