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Economic evaluation alongside randomised controlled trials : design, conduct, analysis, and reporting

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Petrou, Stavros and Gray, Alastair, 1953-. (2011) Economic evaluation alongside randomised controlled trials : design, conduct, analysis, and reporting. BMJ, Vol.342 . d1548. ISSN 0959-8138

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Official URL: http://dx.doi.org/10.1136/bmj.d1548

Abstract

Economic evaluation involves the comparative analysis of the costs and consequences of alternative programmes or interventions. It has increasingly been used to inform decision making about healthcare in the United Kingdom and other industrialised nations. Randomised controlled trials are commonly used as a vehicle for economic evaluations. Indeed, many funders, such as the UK National Institute for Health Research Health Technology Assessment Programme, routinely request that assessments of cost effectiveness are incorporated in the design of randomised trials. This article outlines some of the key issues concerning the design, conduct, analysis, and reporting of economic evaluations based on trials with individual patient data. Economic evaluations that synthesise data from disparate sources using decision analytical models (typically using summary rather than individual patient data) are discussed in an accompanying article.

Item Type:	Journal Article
Subjects:	R Medicine > RA Public aspects of medicine
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Medical economics, Clinical trials, Research -- Methodology, Medical care, Cost of -- Research
Journal or Publication Title:	BMJ
Publisher:	BMJ Group
ISSN:	0959-8138
Date:	7 April 2011
Volume:	Vol.342
Page Range:	d1548
Identification Number:	10.1136/bmj.d1548
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Medical Research Council (Great Britain) (MRC)
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URI:	http://wrap.warwick.ac.uk/id/eprint/37060