The structural identifiability of susceptible–infective–recovered type epidemic models with incomplete immunity and birth targeted vaccination
Chapman, James D. and Evans, N. D.. (2009) The structural identifiability of susceptible–infective–recovered type epidemic models with incomplete immunity and birth targeted vaccination. Biomedical Signal Processing and Control, Vol.4 (No.4). pp. 278-284. ISSN 17468094Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.bspc.2009.02.003
This paper considers the implications of a structural identifiability analysis on a series of fundamental three-compartment epidemic model structures, derived around the general SIR (susceptible–infective–recovered) framework. The models represent various forms of incomplete immunity acquired through natural infection, or from administration of a birth targeted vaccination programme. It is shown that the addition of a vaccination campaign has a negative effect on the structural identifiability of all considered models. In particular, the actual proportion of vaccination coverage achieved, an essential parameter, cannot be uniquely estimated from even ideal prevalence data.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RA Public aspects of medicine
T Technology > TA Engineering (General). Civil engineering (General)
|Divisions:||Faculty of Science > Engineering
Faculty of Science > WMG (Formerly the Warwick Manufacturing Group)
|Library of Congress Subject Headings (LCSH):||Communicable diseases -- Epidemiology -- Mathematical models, Vaccination|
|Journal or Publication Title:||Biomedical Signal Processing and Control|
|Official Date:||October 2009|
|Page Range:||pp. 278-284|
|Access rights to Published version:||Restricted or Subscription Access|
Special Issue on Biomedical Systems, Signals and Control. Selected papers from the IFAC World Congress, Seoul, July 2008.
|Funder:||Engineering and Physical Sciences Research Council (EPSRC)|
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