Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Intrinsic dynamics of heart regulatory systems on short timescales : from experiment to modelling

Tools
- Tools
+ Tools

Khovanov, I. A., Khovanova, N. A., McClintock, P. V. E. and Stefanovska, A. (2009) Intrinsic dynamics of heart regulatory systems on short timescales : from experiment to modelling. Journal of Statistical Mechanics: Theory and Experiment, Vol.2009 (No.1). Article: P01016. doi:10.1088/1742-5468/2009/01/P01016 ISSN 1742-5468.

[img]
Preview
PDF
WRAP_Khovanova_0973918-es-121211-n.khovanova0901.pdf - Accepted Version - Requires a PDF viewer.

Download (383Kb)
Official URL: http://dx.doi.org/10.1088/1742-5468/2009/01/P01016

Request Changes to record.

Abstract

We discuss open problems related to the stochastic modelling of cardiac function. The work is based on an experimental investigation of the dynamics of heart rate variability (HRV) in the absence of respiratory perturbations. We consider first the cardiac control system on short timescales via an analysis of HRV within the framework of a random walk approach. Our experiments show that HRV on timescales of less than a minute takes the form of free diffusion, close to Brownian motion, which can be described as a non-stationary process with stationary increments. Secondly, we consider the inverse problem of modelling the state of the control system so as to reproduce the experimentally observed HRV statistics of. We discuss some simple toy models and identify open problems for the modelling of heart dynamics.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics
Q Science > QP Physiology
Divisions: Faculty of Science, Engineering and Medicine > Engineering > Engineering
Library of Congress Subject Headings (LCSH): Heart -- Mathematical models, Heart beat -- Mathematical models
Journal or Publication Title: Journal of Statistical Mechanics: Theory and Experiment
Publisher: Institute of Physics Publishing Ltd.
ISSN: 1742-5468
Official Date: January 2009
Dates:
DateEvent
January 2009Published
Volume: Vol.2009
Number: No.1
Number of Pages: 15
Page Range: Article: P01016
DOI: 10.1088/1742-5468/2009/01/P01016
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 17 December 2015
Date of first compliant Open Access: 17 December 2015
Funder: Engineering and Physical Sciences Research Council (EPSRC), Wellcome Trust (London, England)

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us