Holt, Tim A. (2009) Use of primary care data for identifying individuals at risk of cardiovascular disease. PhD thesis, University of Warwick.

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Abstract

The aim of this research was to explore the potential of routinely collected primary care data to support the identification of individuals for cardiovascular risk reduction. The work involved a systematic literature review of reminder interventions operating at the point of care; a randomised controlled trial of a novel software tool to facilitate the targeting of individuals at risk of cardiovascular disease; and an exploration of qualitative issues relevant to the challenge of cardiovascular risk reduction in current practice. The Systematic review resulted in a narrative synthesis and a meta-analysis. It concluded that reminder interventions are generally effective at changing practitioner behaviour, but the effect is inconsistent, probably dependent on organisational context, and difficult to predict. The e-Nudge trial involved 19 practices in Coventry and Warwickshire, who used the e-Nudge software tool for two years. This tool was programmed for the project by the clinical software company EMIS. Whilst the primary outcome (cardiovascular event rate) was not significantly reduced in this timescale, a beneficial effect was demonstrated on the adequacy of data to support risk estimation and on the visibility of the at risk population. A new means of addressing the problem of undiagnosed and late-diagnosed diabetes was also discovered. Qualitative aspects of this area of care are presented through a discussion of ethical issues, a limited series of interviews with members of the public included in the appendix, and extensive field notes taken throughout the research. These provide some context in support of the e-Nudge trial. Routinely collected data of UK general practice provide a potentially rich resource to support primary cardiovascular disease prevention, but practical, ethical and conceptual issues must all be addressed to optimise their impact. This conclusion forms the thesis to be explored and justified through this dissertation.

Item Type:	Thesis or Dissertation (PhD)
Subjects:	R Medicine > RC Internal medicine
Library of Congress Subject Headings (LCSH):	Cardiovascular system -- Diseases -- Diagnosis, Primary care (Medicine) -- Databases, Primary care (Medicine) -- Software
Date:	December 2009
Institution:	University of Warwick
Theses Department:	Warwick Medical School
Thesis Type:	PhD
Publication Status:	Unpublished
Supervisor(s)/Advisor:	Thorogood, Margaret ; Griffiths, Frances
Extent:	xxiii, 281, [74] leaves : charts
Language:	eng
URI:	http://wrap.warwick.ac.uk/id/eprint/3727

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