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Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease : evidence from observational studies
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Rees, Karen, Stowe, Rebecca, Patel, Smitaa, Ives, Natalie, Breen, Kieran, Clarke, Carl E. and Ben-Shlomo, Yoav. (2011) Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease : evidence from observational studies. Cochrane Database of Systematic Reviews (No.11). CD008454. ISSN 1469-493X
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Official URL: http://dx.doi.org/10.1002/14651858.CD008454.pub2
Abstract
This is the protocol for a review and there is no abstract. The objectives are as follows: We will address the following questions: 1) Do NSAIDs prevent the onset of Parkinson's disease(PD)? We will seek primary prevention trials and epidemiological studies examining the association between NSAIDs and PD to address this question. 2) Are NSAIDs neuroprotective in PD - do they slow the progression of disease once PD is established? We will seek secondary prevention trials to address this question. We will also explore any adverse effects of taking NSAIDs. 3) What are the adverse effects of taking NSAIDs in PD? We will use studies in question 2 above to examine this, along with any additional studies identified from the searching (including case studies and case series).
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
| Library of Congress Subject Headings (LCSH): | Parkinson's disease, Parkinson's disease -- Prevention -- Research, Nonsteroidal anti-inflammatory agents -- Effectiveness |
| Journal or Publication Title: | Cochrane Database of Systematic Reviews |
| Publisher: | John Wiley & Sons Ltd. |
| ISSN: | 1469-493X |
| Book Title: | Cochrane Database of Systematic Reviews |
| Date: | 9 November 2011 |
| Number: | No.11 |
| Page Range: | CD008454 |
| Identification Number: | 10.1002/14651858.CD008454.pub2 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Description: | Protocol report. |
| Funder: | Parkinson's Disease Society (PDS) |
| URI: | http://wrap.warwick.ac.uk/id/eprint/37305 |
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