Hind, D. (Daniel), Tappenden, P. (Paul), 1980-, Tumur, I., Eggington, S., Sutcliffe, Paul A. and Ryan, A.. (2008) The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer : systematic review and economic evaluation (review of NICE guidance no. 33). Health Technology Assessment, Vol.12 (No.15). pp. 1-182. ISSN 1366-5278

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Abstract

Objectives: To evaluate three technologies for the management of advanced colorectal cancer: (1) first-line irinotecan combination [with 5-fluorouracil (5-FU)] or second-line monotherapy; (2) first- or second-line oxaliplatin combination (again, with 5-FU); and (3) raltitrexed, where 5-FU is inappropriate. To examine the role of irinotecan and oxaliplatin in reducing the extent of incurable disease before curative surgery (downstaging).

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) R Medicine > RM Therapeutics. Pharmacology
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences
Library of Congress Subject Headings (LCSH):	Colon (Anatomy) -- Cancer -- Treatment, Rectum -- Cancer -- Treatment
Journal or Publication Title:	Health Technology Assessment
Publisher:	NIHR Health Technology Assessment programme
ISSN:	1366-5278
Date:	May 2008
Volume:	Vol.12
Number:	No.15
Number of Pages:	182
Page Range:	pp. 1-182
Identification Number:	10.3310/hta12150
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	NIHR Health Technology Assessment Programme (Great Britain)
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URI:	http://wrap.warwick.ac.uk/id/eprint/37389

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