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The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer : systematic review and economic evaluation (review of NICE guidance no. 33)
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Hind, D., Tappenden, P., Tumur, I., Eggington, S., Sutcliffe, P. (Paul) and Ryan, A. (2008) The use of irinotecan, oxaliplatin and raltitrexed for the treatment of advanced colorectal cancer : systematic review and economic evaluation (review of NICE guidance no. 33). Health Technology Assessment, Vol.12 (No.15). pp. 1-182. doi:10.3310/hta12150 ISSN 1366-5278.
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Official URL: http://dx.doi.org/10.3310/hta12150
Abstract
Objectives:
To evaluate three technologies for the management of advanced colorectal cancer: (1) first-line irinotecan combination [with 5-fluorouracil (5-FU)] or second-line monotherapy; (2) first- or second-line oxaliplatin combination (again, with 5-FU); and (3) raltitrexed, where 5-FU is inappropriate. To examine the role of irinotecan and oxaliplatin in reducing the extent of incurable disease before curative surgery (downstaging).
| Item Type: | Journal Article | ||||
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| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) R Medicine > RM Therapeutics. Pharmacology |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) > Warwick Evidence Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Colon (Anatomy) -- Cancer -- Treatment, Rectum -- Cancer -- Treatment | ||||
| Journal or Publication Title: | Health Technology Assessment | ||||
| Publisher: | NIHR Health Technology Assessment programme | ||||
| ISSN: | 1366-5278 | ||||
| Official Date: | May 2008 | ||||
| Dates: |
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| Volume: | Vol.12 | ||||
| Number: | No.15 | ||||
| Number of Pages: | 182 | ||||
| Page Range: | pp. 1-182 | ||||
| DOI: | 10.3310/hta12150 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Date of first compliant deposit: | 1 August 2016 | ||||
| Date of first compliant Open Access: | 1 August 2016 | ||||
| Funder: | NIHR Health Technology Assessment Programme (Great Britain) |
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