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Isolated thyroxine malabsorption treated with intramuscular thyroxine injections
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Anderson, Lydia, Joseph, Franklin, Goenka, Niru and Patel, Vinod. (2009) Isolated thyroxine malabsorption treated with intramuscular thyroxine injections. The American Journal of the Medical Sciences, Vol.337 (No.2). pp. 150-152. ISSN 0002-9629
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Official URL: http://dx.doi.org/10.1097/MAJ.0b013e31817ee556
Abstract
An 18-year-old girl with multiple autoimmune endocrinopathies was referred to the endocrinology clinic for management of hypothyroidism. She required increasing doses of thyroxine but remained hypothyroid. Daily and weekly supervised thyroxine administration strategies were unsuccessful. She was extensively investigated for malabsorption; however, all the results were normal. She was subsequently commenced on weekly intramuscular thyroxine injections and became biochemically and clinically euthyroid. Subsequent elective hospital admission and administration of thyroxine via nasogastric tube resulted in recurrence of her hypothyroidism. This case demonstrates apparent isolated true levothyroxine malabsorption existing in isolation and suggests that intramuscular thyroxine injections may be a useful therapeutic modality in these patients.
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Faculty of Medicine > Warwick Medical School > Institute of Clinical Education (ICE) Faculty of Medicine > Warwick Medical School |
| Library of Congress Subject Headings (LCSH): | Thyroxine, Malabsorption syndromes -- Treatment, Hypothyroidism, Injections, Intramuscular |
| Journal or Publication Title: | The American Journal of the Medical Sciences |
| Publisher: | Lippincott Williams & Wilkins |
| ISSN: | 0002-9629 |
| Date: | February 2009 |
| Volume: | Vol.337 |
| Number: | No.2 |
| Page Range: | pp. 150-152 |
| Identification Number: | 10.1097/MAJ.0b013e31817ee556 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| URI: | http://wrap.warwick.ac.uk/id/eprint/37551 |
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