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UK DRAFFT : a randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius
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Costa, Matthew L., Achten, Juul, Parsons, Nicholas R., Rangan, Amar, Edlin, Richard P., Brown, Jaclyn and Lamb, S. E. (Sallie E.) (2011) UK DRAFFT : a randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius. BMC Musculoskeletal Disorders, Vol.12 (No.1). p. 201. doi:10.1186/1471-2474-12-201
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WRAP_Lamb_1471-2474-12-201.pdf - Published Version Download (253Kb) |
Official URL: http://dx.doi.org/10.1186/1471-2474-12-201
Abstract
Background: Fractures of the distal radius are extremely common injuries in adults. However, the optimal
management remains controversial. In general, fractures of the distal radius are treated non-operatively if the bone
fragments can be held in anatomical alignment by a plaster cast or orthotic. However, if this is not possible, then
operative fixation is required. There are several operative options but the two most common in the UK, are
Kirschner-wire fixation (K-wires) and volar plate fixation using fixed-angle screws (locking-plates). The primary aim of
this trial is to determine if there is a difference in the Patient-Reported Wrist Evaluation one year following K-wire
fixation versus locking-plate fixation for adult patients with a dorsally-displaced fracture of the distal radius.
Methods/design: All adult patients with an acute, dorsally-displaced fracture of the distal radius, requiring
operative fixation are potentially eligible to take part in this study. A total of 390 consenting patients will be
randomly allocated to either K-wire fixation or locking-plate fixation. The surgery will be performed in trauma units
across the UK using the preferred technique of the treating surgeon. Data regarding wrist function, quality of life,
complications and costs will be collected at six weeks and three, six and twelve months following the injury. The
primary outcome measure will be wrist function with a parallel economic analysis.
Discussion: This pragmatic, multi-centre trial is due to deliver results in December 2013.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RD Surgery | ||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit |
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| Library of Congress Subject Headings (LCSH): | Wrist -- Fractures -- Treatment, Bone wiring (Orthopedics), Bone screws (Orthopedics) | ||||
| Journal or Publication Title: | BMC Musculoskeletal Disorders | ||||
| Publisher: | BioMed Central Ltd. | ||||
| ISSN: | 1471-2474 | ||||
| Official Date: | 13 September 2011 | ||||
| Dates: |
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| Volume: | Vol.12 | ||||
| Number: | No.1 | ||||
| Page Range: | p. 201 | ||||
| DOI: | 10.1186/1471-2474-12-201 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access | ||||
| Funder: | National Institute for Health Research (Great Britain) (NIHR) | ||||
| Grant number: | HTA08/116/97 (NIHR) |
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