Common variation at 10p12.31 near MLLT10 influences meningioma risk
. (2011) Common variation at 10p12.31 near MLLT10 influences meningioma risk. Nature Genetics, Vol.43 (No.9). pp. 825-827. ISSN 1061-4036 Full text not available from this repository.
Official URL: http://dx.doi.org/10.1038/ng.879
To identify susceptibility loci for meningioma, we conducted a genome-wide association study of 859 affected individuals (cases) and 704 controls with validation in two independent sample sets totaling 774 cases and 1,764 controls. We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)). This finding advances our understanding of the genetic basis of meningioma development.
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