Ring-opening polymerization of an O-carboxyanhydride monomer derived from l-malic acid
Pounder, Ryan J., Fox, D. J. (David J.), Barker, Ian A., Bennison, Michael J. and Dove, Andrew P.. (2011) Ring-opening polymerization of an O-carboxyanhydride monomer derived from l-malic acid. Polymer Chemistry, Vol.2 (No.10). pp. 2204-2212. ISSN 1759-9954Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/c1py00254f
The synthesis and ring-opening polymerization (ROP) of an O-carboxyanhydride (OCA) monomer derived from L-malic acid (L-malOCA) is reported. Application of 4-dimethylaminopyridine as catalyst led to the observation of a number of undesirable side products. Investigation of different para-substituted pyridines as catalysts identified 4-methoxypyridine to have the ideal balance of activity and selectivity to enable the controlled ROP of L-malOCA. Deprotection of the benzyl ester side groups of the resultant polymers was achieved by hydrogenolysis and the resulting hydrophilic poly(a-malic acid) was observed to fully degrade within 7 days in aqueous solution.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Divisions:||Faculty of Science > Chemistry|
|Library of Congress Subject Headings (LCSH):||Ring-opening polymerization, Monomers|
|Journal or Publication Title:||Polymer Chemistry|
|Publisher:||Royal Society of Chemistry|
|Page Range:||pp. 2204-2212|
|Access rights to Published version:||Restricted or Subscription Access|
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