. (2011) Reconstructing the history of maize streak virus strain : a dispersal to reveal diversification hot spots and its origin in Southern Africa. Journal of Virology, Vol.85 (No.18). pp. 9623-9636. ISSN 0022-538X

Full text not available from this repository.

Abstract

Maize streak virus strain A (MSV-A), the causal agent of maize streak disease, is today one of the most serious biotic threats to African food security. Determining where MSV-A originated and how it spread transcontinentally could yield valuable insights into its historical emergence as a crop pathogen. Similarly, determining where the major extant MSV-A lineages arose could identify geographical hot spots of MSV evolution. Here, we use model-based phylogeographic analyses of 353 fully sequenced MSV-A isolates to reconstruct a plausible history of MSV-A movements over the past 150 years. We show that since the probable emergence of MSV-A in southern Africa around 1863, the virus spread transcontinentally at an average rate of 32.5 km/year (95% highest probability density interval, 15.6 to 51.6 km/year). Using distinctive patterns of nucleotide variation caused by 20 unique intra-MSV-A recombination events, we tentatively classified the MSV-A isolates into 24 easily discernible lineages. Despite many of these lineages displaying distinct geographical distributions, it is apparent that almost all have emerged within the past 4 decades from either southern or east-central Africa. Collectively, our results suggest that regular analysis of MSV-A genomes within these diversification hot spots could be used to monitor the emergence of future MSV-A lineages that could affect maize cultivation in Africa.

Item Type:	Journal Article
Subjects:	Q Science > QR Microbiology > QR355 Virology S Agriculture > SB Plant culture
Divisions:	Faculty of Science > Life Sciences (2010- ) > Warwick HRI (2004-2010)
Library of Congress Subject Headings (LCSH):	Corn -- Virus diseases, Wheat -- Virus diseases, Corn -- Diseases and pests -- Africa, Mosaic viruses, Gene expression, Phylogeography, Cicadulina
Journal or Publication Title:	Journal of Virology
Publisher:	American Society for Microbiology
ISSN:	0022-538X
Official Date:	September 2011
Volume:	Vol.85
Number:	No.18
Page Range:	pp. 9623-9636
Identification Number:	10.1128/JVI.00640-11
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	National Research Foundation (South Africa) (NRF) , University of Cape Town (UCT), Canon Collins Trust (CCT), Carnegie Corporation of New York , Wellcome Trust (London, England), Fonds voor Wetenschappelijk Onderzoek—Vlaanderen [Research Foundation—Flanders] (FWO), GIS Centre de Recherche et de Veille Sanitaire sur les Maladies Emergentes dans l'Ocean Indien (CRVOI), Réunion. Conseil régional
Grant number:	PRAO/AIRD/CRVOI/08/03 (CRVOI)
URI:	http://wrap.warwick.ac.uk/id/eprint/38526

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Actions (login required)

View Item