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Reconstructing the history of maize streak virus strain : a dispersal to reveal diversification hot spots and its origin in Southern Africa
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(2011) Reconstructing the history of maize streak virus strain : a dispersal to reveal diversification hot spots and its origin in Southern Africa. Journal of Virology, Vol.85 (No.18). pp. 9623-9636. doi:10.1128/JVI.00640-11 Research output not available from this repository, contact author.
Official URL: http://dx.doi.org/10.1128/JVI.00640-11
Abstract
Maize streak virus strain A (MSV-A), the causal agent of maize streak disease, is today one of the most serious biotic threats to African food security. Determining where MSV-A originated and how it spread transcontinentally could yield valuable insights into its historical emergence as a crop pathogen. Similarly, determining where the major extant MSV-A lineages arose could identify geographical hot spots of MSV evolution. Here, we use model-based phylogeographic analyses of 353 fully sequenced MSV-A isolates to reconstruct a plausible history of MSV-A movements over the past 150 years. We show that since the probable emergence of MSV-A in southern Africa around 1863, the virus spread transcontinentally at an average rate of 32.5 km/year (95% highest probability density interval, 15.6 to 51.6 km/year). Using distinctive patterns of nucleotide variation caused by 20 unique intra-MSV-A recombination events, we tentatively classified the MSV-A isolates into 24 easily discernible lineages. Despite many of these lineages displaying distinct geographical distributions, it is apparent that almost all have emerged within the past 4 decades from either southern or east-central Africa. Collectively, our results suggest that regular analysis of MSV-A genomes within these diversification hot spots could be used to monitor the emergence of future MSV-A lineages that could affect maize cultivation in Africa.
| Item Type: | Journal Article | ||||
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| Subjects: | Q Science > QR Microbiology > QR355 Virology S Agriculture > SB Plant culture |
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| Divisions: | Faculty of Science > Life Sciences (2010- ) > Warwick HRI (2004-2010) | ||||
| Library of Congress Subject Headings (LCSH): | Corn -- Virus diseases, Wheat -- Virus diseases, Corn -- Diseases and pests -- Africa, Mosaic viruses, Gene expression, Phylogeography, Cicadulina | ||||
| Journal or Publication Title: | Journal of Virology | ||||
| Publisher: | American Society for Microbiology | ||||
| ISSN: | 0022-538X | ||||
| Official Date: | September 2011 | ||||
| Dates: |
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| Volume: | Vol.85 | ||||
| Number: | No.18 | ||||
| Page Range: | pp. 9623-9636 | ||||
| DOI: | 10.1128/JVI.00640-11 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Funder: | National Research Foundation (South Africa) (NRF) , University of Cape Town (UCT), Canon Collins Trust (CCT), Carnegie Corporation of New York , Wellcome Trust (London, England), Fonds voor Wetenschappelijk Onderzoek—Vlaanderen [Research Foundation—Flanders] (FWO), GIS Centre de Recherche et de Veille Sanitaire sur les Maladies Emergentes dans l'Ocean Indien (CRVOI), Réunion. Conseil régional | ||||
| Grant number: | PRAO/AIRD/CRVOI/08/03 (CRVOI) |
Data sourced from Thomson Reuters' Web of Knowledge
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