A transcritical bifurcation in an immune response model
Burroughs, Nigel John, Ferreira, M. (Miguel), Oliveira, Bruno M. P. M. and Pinto, Alberto Adrego. (2011) A transcritical bifurcation in an immune response model. Journal of Difference Equations and Applications, Vol.17 (No.7). pp. 1101-1106. ISSN 1023-6198Full text not available from this repository.
Official URL: http://dx.doi.org/10.1080/10236190903095291
The consequences of regulatory T cell (Treg) inhibition of interleukine 2 secretion are examined by mathematical modelling. We find a transcritical bifurcation that might explain two alternative scenarios: in one case the appearance of autoimmune responses and in another the suppression of the immune response.
|Item Type:||Journal Article|
|Subjects:||Q Science > QA Mathematics
Q Science > QR Microbiology > QR180 Immunology
|Divisions:||Faculty of Science > Mathematics
Faculty of Science > Centre for Systems Biology
|Library of Congress Subject Headings (LCSH):||T cells, Immune response -- Mathematical models, Bifurcation theory, T cells -- Receptors, Immune response -- Regulation|
|Journal or Publication Title:||Journal of Difference Equations and Applications|
|Publisher:||Taylor & Francis Inc.|
|Page Range:||pp. 1101-1106|
|Funder:||Fundação para a Ciência e a Tecnologia (FCT), Portugal. Ministério da Ciência, Tecnologia e Ensino Superior (MCTES), Fundação Calouste Gulbenkian (FCG), Universidade do Minho (UdM), Universidade do Porto (UP)|
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