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Diagnosing the individual to control the epidemic
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Medley, Graham (2011) Diagnosing the individual to control the epidemic. Science Translational Medicine, Vol.3 (No.82). 82ps18. doi:10.1126/scitranslmed.3002441 ISSN 1946-6234.
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Official URL: http://dx.doi.org/10.1126/scitranslmed.3002441
Abstract
When vaccination is not an option, the only way to actively control an epidemic is to identify infectious individuals and "remove" them (by treatment, quarantine, or culling). In a recent Science paper, Charleston et al. present data and an analysis suggesting that clinical diagnosis of foot-and-mouth disease is very closely linked in time to shedding of virus; as such, removal of clinically affected animals might be sufficient to control an epidemic. Although these results are for a veterinary disease, they are very pertinent for all infectious diseases, including those of humans. In this Perspective, we consider the role of experimental research in determining the biology of infection as well as the importance of diagnosis for epidemic control.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||
| Library of Congress Subject Headings (LCSH): | Epidemics, Communicable diseases -- Transmission -- Research, Communicable diseases -- Prevention, Staphylococcus aureus infections -- Prevention, Foot-and-mouth disease -- Diagnosis | ||||
| Journal or Publication Title: | Science Translational Medicine | ||||
| Publisher: | American Association for the Advancement of Science | ||||
| ISSN: | 1946-6234 | ||||
| Official Date: | 11 May 2011 | ||||
| Dates: |
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| Volume: | Vol.3 | ||||
| Number: | No.82 | ||||
| Page Range: | 82ps18 | ||||
| DOI: | 10.1126/scitranslmed.3002441 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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