Medley, Graham (2011) Diagnosing the individual to control the epidemic. Science Translational Medicine, Vol.3 (No.82). 82ps18. doi:10.1126/scitranslmed.3002441

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Abstract

When vaccination is not an option, the only way to actively control an epidemic is to identify infectious individuals and "remove" them (by treatment, quarantine, or culling). In a recent Science paper, Charleston et al. present data and an analysis suggesting that clinical diagnosis of foot-and-mouth disease is very closely linked in time to shedding of virus; as such, removal of clinically affected animals might be sufficient to control an epidemic. Although these results are for a veterinary disease, they are very pertinent for all infectious diseases, including those of humans. In this Perspective, we consider the role of experimental research in determining the biology of infection as well as the importance of diagnosis for epidemic control.

Item Type:	Journal Article
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine
Divisions:	Faculty of Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH):	Epidemics, Communicable diseases -- Transmission -- Research, Communicable diseases -- Prevention, Staphylococcus aureus infections -- Prevention, Foot-and-mouth disease -- Diagnosis
Journal or Publication Title:	Science Translational Medicine
Publisher:	American Association for the Advancement of Science
ISSN:	1946-6234
Official Date:	11 May 2011
Dates:	Date Event 11 May 2011 Published
Volume:	Vol.3
Number:	No.82
Page Range:	82ps18
DOI:	10.1126/scitranslmed.3002441
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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