Nielsen, B. H., Thomsen, P. T., Green, Laura E. and Kaler, Jasmeet. (2012) A study of the dynamics of digital dermatitis in 742 lactating dairy cows. Preventive Veterinary Medicine, Vol.104 (No.1-2). pp. 44-52. ISSN 0167 5877

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Abstract

Digital dermatitis (DD) is a contagious disease of cattle affecting the skin of the claw. The disease presents with a range of severities and can be associated with lameness. Information about the disease dynamics of DD is scarce. Parity and lactation stage have been identified as risk factors for DD and studies have also indicated that not all cows are equal regarding their risk of recurrent disease and prospects for cure from DD. The aim of this study was to investigate host heterogeneity to DD and to identify disease patterns of DD and factors associated with the development and resolution of lesions. In three commercial dairy herds, 742 lactating cows were observed for DD lesions weekly for 11 or 12 weeks. The effects of parity, lactation stage and duration of preceding episode on the hazard of transitions between healthy and lesion states were analysed using a multilevel multistate discrete-time model. One or more DD lesions were observed in 460 cows and lesions were observed in 2426 out of 10585 observations. In total, 1755 uncensored episodes with DD lesions were observed. Early lactation was associated with a reduced risk of developing lesions compared with mid and late lactation. Lesions that developed in late lactation had a greater likelihood of resolution compared with lesions that developed during early lactation. There was a reduced risk of lesions developing in parity 3 compared with parity 1 cows, but an increased risk of lesions developing in parity 2 compared with parity 1 cows. In the present study, the mean duration of uncensored DD episodes was 1.7 weeks indicating that the duration of the majority of DD lesions might be shorter than the 42 days reported previously. The transitions between disease states suggest that DD is a dynamic disease, and that the early stage lesions are more transient than expected from previous studies. We conclude that studies with shorter observation intervals than one week are needed to fully understand and describe the individual and group dynamics of DD.

Item Type:	Journal Article
Subjects:	S Agriculture > SF Animal culture
Divisions:	Faculty of Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH):	Cattle -- Diseases -- Mathematical models, Cattle -- Diseases -- Epidemiology, Skin -- Inflammation, Lactation
Journal or Publication Title:	Preventive Veterinary Medicine
Publisher:	Elsevier
ISSN:	0167 5877
Date:	April 2012
Volume:	Vol.104
Number:	No.1-2
Page Range:	pp. 44-52
Identification Number:	10.1016/j.prevetmed.2011.10.002
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Denmark. Ministeriet for fødevarer, landbrug og fiskeri [Ministry of Food, Agriculture, and Fisheries]
References:	Amory, J.R., Barker, Z.E., Wright, J.L., Mason, S.A., Blowey, R.W., Green, L.E., 2008. Associations between sole ulcer, white line disease and digital dermatitis and the milk yield of 1824 dairy cows on 30 dairy cow farms in England and Wales from February 2003-November 2004. Prev. Vet. Med. 83, 381-391. Barker, Z.E., Amory, J.R., Wright, J.L., Mason, S.A., Blowey, R.W., Green, L.E., 2009. Risk factors for increased rates of sole ulcers, white line disease, and digital dermatitis in dairy cattle from twenty-seven farms in England and Wales. J. Dairy Sci. 92, 1971-1978. Bicalho, R.C., Warnick, L.D., Guard, C.L., 2008. Strategies to Analyze Milk Losses Caused by Diseases with Potential Incidence Throughout the Lactation: A Lameness Example. J. Dairy Sci. 91, 2653-2661. Bruijnis, M.R.N., Hogeveen, H., Stassen, E.N., 2010. Assessing economic consequences of foot disorders in dairy cattle using a dynamic stochastic simulation model. J. Dairy Sci. 93, 2419-2432. Capion, N., Thamsborg, S.M., Enevoldsen, C., 2008. Prevalence of foot lesions in Danish Holstein cows. Vet. Rec. 163, 80-85. Cramer, G., Lissemore, K.D., Guard, C.L., Leslie, K.E., Kelton, D.F., 2008. Herd- and Cow-Level Prevalence of Foot Lesions in Ontario Dairy Cattle. J. Dairy Sci. 91, 3888-3895. de Jesus Argaez-Rodriguez, F., Hird, D.W., de Anda, J.H., Read, D.H., Rodriguez-Lainz, A., 1997. Papillomatous digital dermatitis on a commercial dairy farm in Mexicali, Mexico: Incidence and effect on reproduction and milk production. Prev. Vet. Med. 32, 275-286. Demirkan, I., Carter, S.D., Murray, R.D., Blowey, R.W., Woodward, M.J., 1998. The frequent detection of a treponeme in bovine digital dermatitis by immunocytochemistry and polymerase chain reaction. Vet. Microbiol. 60, 285-292. Dopfer, D., Bennett, T.B., Cook, N.B., 2008. Dynamics of Digital Dermatitis Infection Spread in a Large Freestall Housed Wisconsin Dairy Herd. Proceeding from The 15th International Symposium & the 7th Conference on Lameness in Ruminants, Kuopio, Finland, 9-13 June, 2008. Dopfer, D., ter Huurne, A.A.H.M., Cornelisse, J.L., van Asten, A.J.A.M., Koopmans, A., Meijer, F.A., Schukken, Y.H., Szakall, I., Klee, W., Bosma, R.B., 1997. Histological and bacteriological evaluation of digital dermatitis in cattle, with special reference to spirochaetes and Campylobacter faecalis. Vet. Rec. 140, 620-623. Dopfer, D., van Boven, M.R., de Jong, M.C.M., 2004. A mathematical model for the dynamics of digital dermatitis in groups of cattle to study the effecacy of group-based therapy and prevention strategies. In: Joshi, N.P., Herdt, T.H. (Eds.), Proceedings of the 12th International Conference for Production Diseases in Farm Animals, p. 138. Enting, H., Kooij, D., Dijkhuizen, A.A., Huirne, R.B.M., Noordhuizen-Stassen, E.N., 1997. Economic losses due to clinical lameness in dairy cattle. Livest. Prod. Sci. 49, 259-267. Ettema, J., Østergaard, S.R., Kristensen, A.R., 2010. Modelling the economic impact of three lameness causing diseases using herd and cow level evidence. Prev. Vet. Med. 95, 64-73. Ettema, J.F., Capion, N., Hill, A.E., 2007. The association of hoof lesions at claw trimming with test-day milk yield in Danish Holsteins. Prev. Vet. Med. 79, 224-243. Green, L.E., Hedges, V.J., Schukken, Y.H., Blowey, R.W., Packington, A.J., 2002. The Impact of Clinical Lameness on the Milk Yield of Dairy Cows. J. Dairy Sci. 85, 2250-2256. Holzhauer, M., Dopfer, D., de Boer, J., van Schaik, G., 2008a. Effects of different intervention strategies on the incidence of papillomatous digital dermatitis in dairy cows. Vet. Rec. 162, 41-46. Holzhauer, M., Hardenberg, C., Bartels, C.J.M., Frankena, K., 2006. Herd- and Cow-Level Prevalence of Digital Dermatitis in The Netherlands and Associated Risk Factors. J. Dairy Sci. 89, 580-588. Holzhauer, M., Bartels, C.J.M., Dopfer, D., van Schaik, G., 2008b. Clinical course of digital dermatitis lesions in an endemically infected herd without preventive herd strategies. Vet. J. 177, 222-230. Kaler, J., Medley, G.F., Grogono-Thomas, R., Wellington, E.M., Calvo-Bado, L.A., Wassink, G.J., King, E.M., Moore, L.J., Russell, C., Green, L.E., 2010. Factors associated with changes of state of foot conformation and lameness in a flock of sheep. Prev. Vet. Med 97, 237-244. Klitgaard, K., Boye, M., Capion, N., Jensen, T.K., 2008. Evidence of Multiple Treponema Phylotypes Involved in Bovine Digital Dermatitis as Shown by 16S rRNA Gene Analysis and Fluorescence In Situ Hybridization. J. Clin. Microbiol. 46, 3012-3020. Kristensen, E., Dueholm, L., Vink, D., Andersen, J.E., Jakobsen, E.B., Illum-Nielsen, S., Petersen, F.A., Enevoldsen, C., 2006. Within- and Across-Person Uniformity of Body Condition Scoring in Danish Holstein Cattle. J. Dairy Sci. 89, 3721-3728. Manske, T., Hultgren, J., Bergsten, C., 2002. Topical treatment of digital dermatitis associated with severe heel-horn erosion in a Swedish dairy herd. Prev. Vet. Med. 53, 215-231. Nielsen, B., Thomsen, P., Sorensen, J., 2009. A study of duration of digital dermatitis lesions after treatment in a Danish dairy herd. Acta Vet. Scand. 51, 27. Nowrouzan, I.J. & Radgohar, I., 2011. Restrospective Study of the Correlation Between Hygiene Scores and the Prevalence of Papillomatous Digital Dermatitis in Dairy Cows. Proceeding from The 16th International Symposium & the 8th Conference on Lameness in Ruminants, Rotorua, New Zealand, 29 February-3 March, 2011 Rasbash, J., Steele, F., Browne, W., Prosser, B., 2004. A User's Guide to MLwiN, version 2.10. London: Institute of Education. Rodriguez-Lainz, A., Melendez-Retamal, P., Hird, D.W., Read, D.H., Walker, R.L., 1999. Farm- and host-level risk factors for papillomatous digital dermatitis in Chilean dairy cattle. Prev. Vet. Med 42, 87-97. Somers, J.G.C.J., Frankena, K., Noordhuizen-Stassen, E.N., Metz, J.H.M., 2005a. Risk factors for digital dermatitis in dairy cows kept in cubicle houses in The Netherlands. Prev. Vet. Med. 71, 11-21. Somers, J.G.C.J., Schouten, W.G.P., Frankena, K., Noordhuizen-Stassen, E.N., Metz, J.H.M., 2005b. Development of claw traits and claw lesions in dairy cows kept on different floor systems. J. Dairy Sci. 88, 110-120. Steele, F., Goldstein, H., Browne, W., 2004. A General Multilevel Multistate Competing Risks Model for Event History Data, with an Application to a Study of Contraceptive Use Dynamics. Stat. Model. Steele, F., Kallis, C., Goldstein, H., Joshi, H., 2005. The Relationship between Childbearing and Transitions from Marriage and Cohabitation in Britain. Demography 42, 647-673. Tadich, N., Flor, E., Green, L., 2010. Associations between hoof lesions and locomotion score in 1098 unsound dairy cows. Vet. J. 184, 60-65. Thomsen, P.T., Klaas, I.C., Bach, K., 2008. Scoring of Digital Dermatitis During Milking as an Alternative to Scoring in a Hoof Trimming Chute. J. Dairy Sci. 91, 4679-4682. Yano, T., Moe, K.K., Yamazaki, K., Ooka, T., Hayashi, T., Misawa, N., 2010. Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis. Vet. Microbiol. 143, 352-362.
URI:	http://wrap.warwick.ac.uk/id/eprint/39086

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