Burroughs, Nigel John, Oliveira, B. M. P. M., Pinto, A. A. and Ferreira, M.. (2011) Immune response dynamics. Mathematical and Computer Modelling, Vol.53 (No.7-8). pp. 1410-1419. ISSN 0895-7177

Full text not available from this repository.

Abstract

The consequences of regulatory T cell (Treg) inhibition of interleukine 2 secretion are examined by mathematical modelling. We determine the analytic formula that describes the fine balance between Regulatory T cells and T cells at controlled and immune response equilibrium states. We demonstrate that cytokine dependent growth exhibits a quorum T cell population threshold that determines if immune responses develop on activation. We determine the analytic formulas of T cell proliferation thresholds that allow us to study the sensibility of the quorum growth thresholds controlling immune responses. (C) 2010 Elsevier Ltd. All rights reserved.

Item Type:	Journal Article
Subjects:	Q Science > QA Mathematics
Divisions:	Faculty of Science > Mathematics
Journal or Publication Title:	Mathematical and Computer Modelling
Publisher:	Pergamon
ISSN:	0895-7177
Date:	April 2011
Volume:	Vol.53
Number:	No.7-8
Page Range:	pp. 1410-1419
Identification Number:	10.1016/j.mcm.2010.02.040
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	FCT , Ministerio da Ciencia, Tecnologia e do Ensino Superior , Calouste Gulbenkian Foundation , Centro de Matematica da Universidade do Minho (CMAT), Centro de Matematica da Universidade do Porto (CMUP) , FSE , European Union
URI:	http://wrap.warwick.ac.uk/id/eprint/39814

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item