Reher, Peter, Chrcanovic, Bruno Ramos, Springett, Roger and Harris, Malcolm, 1934-. (2011) Near infrared spectroscopy : a diagnostic tool to evaluate effects of radiotherapy in the mandible? Spectroscopy, Vol.26 (No.1). pp. 11-32. ISSN 0712-4813

Full text not available from this repository.

Abstract

Purpose. This study tests the hypothesis that near infrared spectroscopy can be used to detect changes in haemoglobin oxygenation status in the mandible, and therefore can be used to monitor the deleterious effects of radiotherapy and the possible reversion of these effects with therapeutic ultrasound. Methods. A probe was used to calculate the concentrations of deoxyhaemoglobin in the mandible bone of 30 volunteers with no known malignancies and 10 patients with malignancies in the head and neck region treated with radiotherapy. Results. Although the variability of the measurements was very high, when comparing the right side to the left side of the mandible, the measurements remained relatively similar. There was a great variability between the data for each patient, there was no correlation with age. Conclusions. The near infrared spectroscopy validation for the measurement of deoxyhaemoglobin concentrations in the mandible showed that the variability of the measurements was very high, therefore it is not appropriate to be used diagnostically for the evaluation of radiotherapy effects on the mandibular blood flow and metabolic status.

[error in script] [error in script]

Item Type:	Journal Article
Subjects:	R Medicine > RK Dentistry
Divisions:	Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Near infrared spectroscopy, Mandible, Radiotherapy
Journal or Publication Title:	Spectroscopy
Publisher:	I O S Press
ISSN:	0712-4813
Date:	2011
Volume:	Vol.26
Number:	No.1
Page Range:	pp. 11-32
Identification Number:	10.3233/SPE-2011-0524
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Related URLs:	Publisher
References:	[1] K. Aitasalo and P. Ruotsalainen, Effects of irradiation on mandibular scintigraphy, The Journal of Nuclear Medicine 26 (1985), 1263–1269. [2] J.M. Alexander, Radionuclide bone scanning in the diagnosis of lesions of the maxillofacial region, Journal of Oral Surgery 34 (1976), 249–256. [3] M.R. Beehner and R.E. Marx, Hyperbaric oxygen induced tissue angiogenesis: a human histology and tissue oxygen tension study, in: Proceedings of the 65th Meeting of the American Association of Oral and Maxillofacial Surgeons, Abstracts from the Scientific Sessions, AAOMS, Rosemont, 1983, pp. 78–79. [4] J.E. Brazy, D.V. Lewis, M.H. Mitnick and F.F. Jöbsis van der Vliet, Noninvasive monitoring of cerebral oxygenation in preterm infants: preliminary observations, Pediatrics 75 (1985), 217–225. [5] M.J. Buono, P.W. Miller, C. Hom, R.S. Pozos and F.W. Kolkhorst, Skin blood flow affects in vivo near-infrared spectroscopy measurements in human skeletal muscle, The Japanese Journal of Physiology 55 (2005), 241–244. [6] S. Cade, Malignant Disease and its Treatment by Radium, 2nd edn, Vol. 1, Simukin Marshall, London, 1941. [7] C.B. Cairns, D. Fillipo and H.J. Proctor, A noninvasive method for measuring the effects of increased intracranial pressure with near infrared spectroscopy, Surgery Gynecology and Obstetrics 161 (1985), 145–148. [8] T.R. Cheatle, L.A. Potter, M. Cope, D.T. Delpy, P.D.C. Smith and J.H. Scurr, Near-infrared spectroscopy in peripheral vascular disease, British Journal of Surgery 78 (1991) 405–408. [9] L.P. Choo-Smith, C.C. Dong, B. Cleghorn and M. Hewko, Shedding new light on early caries detection, Journal of the Canadian Dental Association 74 (2008), 913–918. [10] B. Cohen andW.H. Stephenson, Post-irradiation fractures of the neck of the femur, The Journal of Bone and Joint Surgery, British Volume 38-B (1956), 830–845. [11] C.E. Cooper, D.T. Delpy and E.M. Nemoto, The relationship of oxygen delivery to absolute haemoglobin oxygenation and mitochondrial cytochrome oxidase redox state in the adult brain: a near-infrared spectroscopy study, The Biochemical Journal 332 (1998), 627–632. [12] M. Cope, The development of a near infrared spectroscopy system and its application for non invasive monitoring of cerebral blood and tissue oxygenation in the newborn infant, PhD thesis, University of London, 1991. [13] M. Cope and D.T. Delpy, A system for long term measurement of cerebral blood and tissue oxygenation in newborn infants by near infrared transillumination, Medical and Biological Engineering and Computing 26 (1988), 289–294. [14] A. Dullenkopf, U. Lohmeyer, B. Salgo, A.C. Gerber and M. Weiss, Non-invasive monitoring of haemoglobin concentration in paediatric surgical patients using near-infrared spectroscopy, Anaesthesia 59 (2004), 453–458. [15] A.D. Edwards, J.S.Wyatt, C.E. Richardson, D.T. Delpy, M. Cope and E.O.R. Reynolds, Cotside measurements of cerebral blood flow in ill new-born infants by near infrared spectroscopy, The Lancet 2 (1988), 770–771. [16] C.E. Elwell, A Practical User’s Guide to Near Infrared Spectroscopy, UCL Reprographics, Hamamatsu, London, 1995. [17] J.B. Epstein, G. Rea, F.L.W. Wong, J. Spinelli and P. Stevenson-Moore, Osteonecrosis: study of the relationship of dental extractions in patients receiving radiotherapy, Head and Neck Surgery 10 (1987), 48–54. [18] J.B. Epstein, F.L.W. Wong, A. Dickens, I. Szasz and M. Lepawsky, Bone and gallium scans in postradiotherapy osteonecrosis of the jaw, Head and Neck 14 (1992), 288–292. [19] M. Ethunandan, A. Birch, B.T. Evans and J.R. Goddard, Doppler sonography for the assessment of central mandibular blood flow, British Journal of Oral and Maxillofacial Surgery 38 (2000), 294–298. [20] J. Ewing, Tissue reactions to radiation, American Journal of Roentgenology 15 (1926), 93–114. [21] M. Ferrari, C. DeMarchis, A. Di-Nichola, R. Agostino, S. Nodaris and G. Bucci, Cerebral blood volume and haemoglobin oxygen saturation monitoring in neonatal brain by near infrared spectroscopy, Advances in Experimental Medicine and Biology 200 (1986), 203–211. [22] M. Fujita, K. Harada, N. Masaki, K. Shimizutani, S.W. Kim, N. Fujita, K. Sakurai, H. Fuchihata, T. Inone and T. Kozuka, MR imaging of osteoradionecrosis of the mandible following radiotherapy for head and neck cancer SM, Nippon Acta Radiological 51 (1991), 892–900. [23] C.M. Gardner, H. Tan, E.L. Hull, J.B. Lisauskas, S.T. Sum, T.M. Meese, C. Jiang, S.P. Madden, J.D. Caplan, A.P. Burke, R. Virmani, J. Goldstein and J.E. Muller, Detection of lipid core coronary plaques in autopsy specimens with a novel catheter-based near-infrared spectroscopy system, Journal of the American College of Cardiology: Cardiovascular Imaging 1 (2008), 638–648. [24] D.H. Glaister, Current and emerging technology in G-LOC detection: noninvasive monitoring of cerebral microcirculation using near infrared, Aviation, Space, and Environmental Medicine 59 (1988), 23–28. [25] N.B. Hampson and C.A. Piantadosi, Near infrared monitoring of human skeletal muscle oxygenation during forearm ischaemia, Journal of Applied Physiology 64 (1988), 2449–2457. [26] R. Hermans, E. Fossion, C. Ioannides,W. Van den Bogaert, J. Ghekiere and A.L. Baert, CT findings in osteoradionecrosis of the mandible, Skeletal Radiology 25 (1996), 31–36. [27] W. Herschel, Experiments on the refrangibility of the invisible rays of the Sun, Philosophical Transaction of the Royal Society (London) 90 (1800), 284–292. [28] W. Herschel, Experiments on the solar, and on the terrestrial rays that occasion heat; with a comparative view of the laws to which light and heat, or rather the rays which occasion them, are subject, in order to determine whether they are the same, or different. Part I, Philosophical Transaction of the Royal Society (London) 90 (1800), 293–326. [29] W. Herschel, Experiments on the solar, and on the terrestrial rays that occasion heat; with a comparative view of the laws to which light and heat, or rather the rays which occasion them, are subject, in order to determine whether they are the same, or different. Part II, Philosophical Transaction of the Royal Society (London) 90 (1800), 437–538. [30] S. Homma, T. Fukunaga and A. Kagaya, Influence of adipose thickness on near infrared spectroscopic signals in the measurement of human muscle, Journal of Biomedical Optics 1 (1996), 418–424. [31] R. Hull, H. Bortfeld and S. Koons, Near-infrared spectroscopy and cortical responses to speech production, The Open Neuroimaging Journal 3 (2009), 26–30. [32] T.J. Huppert, S.G. Diamond, M.A. Franceschini and D.A. Boas, HomER: a review of time-series analysis methods for near-infrared spectroscopy of the brain, Applied Optics 48 (2009), D280–D298. [33] I.L. Hutchinson, Complications of radiotherapy in the head and neck: an orofacial surgeon’s view, in: Current Radiation Oncology, J.S. Tobias and P.R.M. Thomas, eds, Arnold, London, 1996, pp. 144–177. [34] I.L. Hutchinson, M. Colpe, D.T. Delpy, C.E. Richardson and M. Harris, The investigation of osteoradionecrosis of the mandible by near infrared spectroscopy, British Journal of Oral and Maxillofacial Surgery 28 (1990), 150–154. [35] I.L. Hutchinson, I.D. Cullum, J.A. Langford, P.H. Jarritt, P.J. Ell and M. Harris, The investigation of osteoradionecrosis of the mandible by 99mTc-methylene diphosphonate radionuclide bone scans, British Journal of Oral and Maxillofacial Surgery 28 (1990), 143–149. [36] F.F. Jobsis, Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters, Science 198 (1977), 1264–1267. [37] W. Kaye, Near-infrared spectroscopy, Spectrochimica Acta 6 (1954), 257–287. [38] W. Kaye, Near-Infrared Spectroscopy II. Instrumentation and Technique, Spectrochimica Acta 7 (1955), 181–204. [39] J.G. Kim and H. Liu, Variation of haemoglobin extinction coefficients can cause errors in the determination of haemoglobin concentration measured by near-infrared spectroscopy, Physics in Medicine and Biology 52 (2007), 6295– 6322. [40] M.A. King, D.A. Weber, G.W. Casaretti, F.A. Burgener and O. Corrivean, A study of irradiated bone. Part II: Changes in Tc-99m pyrophosphate bone imaging, The Journal of Nuclear Medicine 21 (1980), 22–30. [41] G. Kok, Spontaneous fractures of the femoral neck after the intensive irradiation of carcinoma of the uterus, Acta Radiological 40 (1953), 511–527. [42] T.S. Leung, C.E. Elwell and D.T. Delpy, Estimation of cerebral oxy- and deoxy-haemoglobin concentration changes in a layered adult head model using near-infrared spectroscopy and multivariate statistical analysis, Physics in Medicine and Biology 50 (2005), 5783–5798. [43] L.N. Livera, Y.A. Wickramasinghe, S.A. Spencer, P. Rolfe and M.S. Thomiley, Cyclical fluctuations in cerebral blood volume, Archives of Disease in Childhood 67 (1992), 62–63. [44] R.E. Marx, Osteonecrosis of the jaws: a review and update, HBO Review 5 (1984), 78–127. [45] S.J. Matcher and C.E. Cooper, Absolute quantification of deoxyhaemoglobin concentration in tissue using near infrared spectroscopy, Physics in Medicine and Biology 39 (1994), 1295–1312. [46] P. Maurer and L. Meyer, Osteoradionecrosis of the mandible – resection aided by measurement of partial pressure of oxygen (pO2): a technical report, Journal of Oral and Maxillofacial Surgery 64 (2006), 560–562. [47] P. Maurer, L. Meyer, A.W. Eckert, M. Berginski and J. Schubert, Measurement of oxygen partial pressure in the mandibular bone using a polarographic fine needle probe, International Journal of Oral and Maxillofacial Surgery 35 (2006), 231–236. [48] K. McCully, L. Landsberg, M. Suarez, M. Hofmann and J. Posner, Identification of peripheral vascular disease in elderly subjects with optical spectroscopy, The Journals of Gerontology: Series A, Biological Sciences and Medical Sciences 52 (1997), B159–B165. [49] A.D. McGregor and D.G. MacDonald, Post irradiation changes in the blood vessels of the adult human mandibles, British Journal of Oral and Maxillofacial Surgery 33 (1995), 15–18. [50] L. Meyer, P. Maurer and J. Schubert, Measurement of oxygen tension in bone. A new method and preliminary results, Journal of Oral and Maxillofacial Surgery 61(Suppl. 1) (2003), 30a. [51] H. Minn, K. Aitasalo and R.P. Happonen, Detection of cancer recurrence in irradiated mandible using positron emission tomography, European Archives of Oto-Rhin-Laryngology 250 (1993), 312–315. [52] S.E. Nicklin, I.A. Hassan, Y.A.Wickramasinghe and S.A. Spencer, The light still shines, but not that brightly? The current status of perinatal near infrared spectroscopy, Archives of Disease in Childhood. Fetal and Neonatal Edition 88 (2003), F263–F268. [53] T. Semerigidis, E. Vairaktaris, I. Iatrou and C.Martis, Blood supply to the oral andmaxillofacial tissues following radiation therapy: a prospective ultrasonographic study, Journal of Craniomaxillofacial Surgery 24 (1996), 16–23. [54] M.S. Shuler, W.M. Reisman, T.E. Whitesides Jr, T.L. Kinsey, E.M. Hammerberg, M.G. Davila and T.J. Moore, Nearinfrared spectroscopy in lower extremity trauma, The Journal of Bone and Joint Surgery. American Volume 91 (2009), 1360–1368. [55] M.B. Taylor and J.G. Whitman, The current status of pulse oxymetry. Clinical value of continuous non-invasive oxygen saturation monitoring, Anaesthesia 41 (1986), 943–949. [56] H. Telfah, Changes in blood flow, tissue metabolism and fat content in the irradiated mandible detected by means of near infrared spectroscopy (NIRS), MSc dissertation, Eastman Dental Institute, University of London, 1995, pp. 1–135. [57] J.J. Thorn, F. Kallehave, P. Westergaard, E.H. Hansen and F. Gottrup, The effect of hyperbaric oxygen on irradiated tissues: transmucosal oxygen tension measurements, Journal of Oral and Maxillofacial Surgery 55 (1997), 1103–1107. [58] J.D. Tobias, G.A. Johnson, S. Rehman, R. Fisher and N. Caron, Cerebral oxygenation monitoring using near infrared spectroscopy during one-lung ventilation in adults, Journal of Minimal Access Surgery 4 (2008), 104–107. [59] S. Waxman, S.R. Dixon, P. L’Allier, J.W. Moses, J.L. Petersen, D. Cutlip, J.C. Tardif, R.W. Nesto, J.E. Muller, M.J. Hendricks, S.T. Sum, C.M. Gardner, J.A. Goldstein, G.W. Stone and M.W. Krucoff, In vivo validation of a catheter-based near-infrared spectroscopy system for detection of lipid core coronary plaques: initial results of the SPECTACL study, Journal of the American College of Cardiology: Cardiovascular Imaging 2 (2009), 858–868. [60] J.S. Wyatt, M. Cope, D.T. Delpy, S. Wray and E.O.R. Reynolds, Quantification of cerebral oxygenation and haemodynamics in sick newborn infants by near infrared spectrophotometry, The Lancet 2 (1986), 1063–1066. [61] J.S. Wyatt, A.D. Edwards, D. Azzopardi and E.O.R. Reynolds, Magnetic resonance and near infrared spectroscopy for investigation of perinatal hypoxic-ischaemic brain injury, Archives of Disease in Childhood 64 (1989), 953–963.
URI:	http://wrap.warwick.ac.uk/id/eprint/39906

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item