Mixed anxiety and depressive disorder outcomes : prospective cohort study in primary care
Walters, K., Buszewicz, M., Weich, Scott and King, Michael B.. (2011) Mixed anxiety and depressive disorder outcomes : prospective cohort study in primary care. The British Journal of Psychiatry, Vol.198 (No.6). pp. 472-478. ISSN 0007-1250Full text not available from this repository.
Official URL: http://dx.doi.org/10.1192/bjp.bp.110.085092
Mixed anxiety and depressive disorder (MADD) is common yet ill-defined, with little known about outcomes.
To determine MADD outcomes over 1 year.
We recruited 250 adults attending seven London general practices with mild moderate distress. Three groups were defined using a diagnostic interview: MADD, other ICD-10 psychiatric diagnosis, no psychiatric diagnosis. We assessed symptoms of distress (General Health Questionnaire-28), quality of life (12-item Short Form Health Survey), general practitioner (GP) diagnosis and consultation rate at baseline, 3 months and 1 year.
Two-thirds of participants with MADD had no significant psychological distress at 3 months (61%) or 1 year (69%). However, compared with those with no diagnosis, individuals had twice the risk of significant distress (incidence rate ratio 2.39, 95% CI 1.29-4.42) at 3 months but not 1 year, and persistently lower quality of life (mental health functioning). There was no significant difference in GP consultation rate/diagnosis.
The majority with MADD improved, but individuals had an increased risk of significant distress at 3 months and a lower quality of life. As we cannot currently predict those with a poorer prognosis these patients should be actively monitored in primary care.
|Item Type:||Journal Article|
|Subjects:||B Philosophy. Psychology. Religion > BF Psychology
R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
|Divisions:||Faculty of Medicine > Warwick Medical School|
|Library of Congress Subject Headings (LCSH):||Anxiety, Depression, Mental, Cohort analysis, Primary care (Medicine)|
|Journal or Publication Title:||The British Journal of Psychiatry|
|Publisher:||Royal College of Psychiatrists|
|Official Date:||June 2011|
|Page Range:||pp. 472-478|
|Funder:||Medical Research Council (Great Britain) (MRC)|
|Grant number:||G106/1053 (MRC)|
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