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Critical illness-induced dysglycaemia : diabetes and beyond

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Smith, F. Gao (Fang Gao), Sheehy, Ann M., Vincent, J. L. and Coursin, Douglas B.. (2010) Critical illness-induced dysglycaemia : diabetes and beyond. Critical Care, Vol.14 (No.6). p. 327. ISSN 1364-8535

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Official URL: http://dx.doi.org/10.1186/cc9266

Abstract

Type 2 diabetes has reached epidemic proportions in many parts of the world. The disease is projected to continue to increase and double within the foreseeable future. Dysglycaemia develops in the form of hyperglycaemia, hypoglycaemia and marked glucose variability in critically ill adults whether they are known to have premorbid diabetes or not. Patients with such glucose dysregulation have increased morbidity and mortality. Whether this is secondary to cause and eff ect from dysglycaemia or is just related to critical illness remains under intense investigation. Identifi cation of intensive care unit (ICU) patients with unrecognised diabetes remains a challenge. Further, there are few data regarding the development of type 2 diabetes in survivors after hospital discharge. This commentary introduces the concept of critical illness-induced dysglycaemia as an umbrella term that includes the spectrum of abnormal glucose homeostasis in the ICU. We outline the need for further studies in the area of glucose regulation and for follow-up of the natural history of abnormal glucose control during ICU admission and beyond.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Non-insulin-dependent diabetes, Blood sugar -- Abnormalities, Critical care medicine
Journal or Publication Title:	Critical Care
Publisher:	BioMed Central Ltd.
ISSN:	1364-8535
Date:	5 November 2010
Volume:	Vol.14
Number:	No.6
Page Range:	p. 327
Identification Number:	10.1186/cc9266
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
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URI:	http://wrap.warwick.ac.uk/id/eprint/40179