The Library
Adhesion of preosteoblasts and fibroblasts onto poly(pentafluorostyrene)-based glycopolymeric films and their biocompatibility
Tools
Babiuch, Krzysztof, Becer, C. Remzi, Gottschaldt, Michael, Delaney, Joseph T., Weisser, Jürgen, Beer, Birgitt, Wyrwa, Ralf, Schnabelrauch, Matthias and Schubert, Ulrich S. (2011) Adhesion of preosteoblasts and fibroblasts onto poly(pentafluorostyrene)-based glycopolymeric films and their biocompatibility. Macromolecular Bioscience, Vol.11 (No.4). pp. 535-548. doi:10.1002/mabi.201000374 ISSN 1616-5187.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1002/mabi.201000374
Abstract
An efficient and metal-catalyst free method of glycopolymer synthesis via thiol/para-fluorine “click” reaction was used to graft acetylated 1-thio-β-d-glucopyranose and 1-thio-β-d-galactopyranose onto a homopolymer of pentafluorostyrene (PFS) as well as onto a block copolymer of styrene and PFS. Subsequent deprotection of the carbohydrate moieties yielded well-defined, sugar-modified polymers (PDI < 1.2). The prepared polymers were not cytotoxic against 3T3 fibroblasts and MC3T3-E1 preosteoblasts. Furthermore, the water-insoluble copolymers were drop-cast and examined as synthetic biocompatible coatings on poly(propylene) substrates for culturing the investigated cell types. Both fibro- and preosteoblasts showed stable adhesion and proliferation on the glycopolymer-coated surfaces.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Glycomics, Polymers, Polymerization, Thin films, Fibroblasts -- Adhesion | ||||
Journal or Publication Title: | Macromolecular Bioscience | ||||
Publisher: | Wiley - V C H Verlag GmbH & Co. KGaA | ||||
ISSN: | 1616-5187 | ||||
Official Date: | 2011 | ||||
Dates: |
|
||||
Volume: | Vol.11 | ||||
Number: | No.4 | ||||
Page Range: | pp. 535-548 | ||||
DOI: | 10.1002/mabi.201000374 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Funder: | Dutch Polymer Institute (DPI) |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |